The Z Mutation Alters the Global Structural Dynamics of α1-Antitrypsin

Open Access

Peer-reviewed

Research Article

The Z Mutation Alters the Global Structural Dynamics of α₁-Antitrypsin

Victoria A. Hughes,

Affiliation Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia
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Robert Meklemburg,

Affiliation Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, United States of America
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Stephen P. Bottomley,

Affiliation Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia
⨯
Patrick L. Wintrode

* E-mail: pwintrode@rx.umaryland.edu

Affiliation Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, United States of America
⨯

Deuterium
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Polymerization
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Hydrogen bonding
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Hydrogen
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Pepsins
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Amides
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Crystal structure
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High performance liquid chromatography
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