Effects of Leucine Supplementation and Serum Withdrawal on Branched-Chain Amino Acid Pathway Gene and Protein Expression in Mouse Adipocytes

Abderrazak Kitsy; Skyla Carney; Juan C. Vivar; Megan S. Knight; Mildred A. Pointer; Judith K. Gwathmey; Sujoy Ghosh

doi:10.1371/journal.pone.0102615

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Research Article

Effects of Leucine Supplementation and Serum Withdrawal on Branched-Chain Amino Acid Pathway Gene and Protein Expression in Mouse Adipocytes

Abderrazak Kitsy ,

Contributed equally to this work with: Abderrazak Kitsy, Skyla Carney

Affiliation Division of Cardiometabolic Disorders, Biomedical Biotechnology Research Institute, North Carolina Central University, Durham, North Carolina, United States of America
⨯
Skyla Carney ,

Contributed equally to this work with: Abderrazak Kitsy, Skyla Carney

Affiliation Division of Cardiometabolic Disorders, Biomedical Biotechnology Research Institute, North Carolina Central University, Durham, North Carolina, United States of America
⨯
Juan C. Vivar,

Affiliation Division of Cardiometabolic Disorders, Biomedical Biotechnology Research Institute, North Carolina Central University, Durham, North Carolina, United States of America
⨯
Megan S. Knight,

Affiliation Division of Cardiometabolic Disorders, Biomedical Biotechnology Research Institute, North Carolina Central University, Durham, North Carolina, United States of America
⨯
Mildred A. Pointer,

Affiliation Division of Cardiometabolic Disorders, Biomedical Biotechnology Research Institute, North Carolina Central University, Durham, North Carolina, United States of America
⨯
Judith K. Gwathmey,

Affiliation Boston University School of Medicine, Boston, Massachusetts, United States of America
⨯
Sujoy Ghosh

* E-mail: sujoy.ghosh@duke-nus.edu.sg

Affiliations Division of Cardiometabolic Disorders, Biomedical Biotechnology Research Institute, North Carolina Central University, Durham, North Carolina, United States of America, Program in Cardiovascular and Metabolic Disorders, Duke-NUS Graduate Medical School, Singapore, Singapore
⨯

Effects of Leucine Supplementation and Serum Withdrawal on Branched-Chain Amino Acid Pathway Gene and Protein Expression in Mouse Adipocytes

Abderrazak Kitsy,
Skyla Carney,
Juan C. Vivar,
Megan S. Knight,
Mildred A. Pointer,
Judith K. Gwathmey,
Sujoy Ghosh

Published: July 22, 2014
https://doi.org/10.1371/journal.pone.0102615

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Leucine
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Adipocyte differentiation
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Adipocytes
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Protein metabolism
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Protein expression
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