Single Nucleotide Polymorphisms with Cis-Regulatory Effects on Long Non-Coding Transcripts in Human Primary Monocytes

Jonas Carlsson Almlöf; Per Lundmark; Anders Lundmark; Bing Ge; Tomi Pastinen; Cardiogenics Consortium; Alison H. Goodall; François Cambien; Panos Deloukas; Willem H. Ouwehand; Ann-Christine Syvänen

doi:10.1371/journal.pone.0102612

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Open Access

Peer-reviewed

Research Article

Single Nucleotide Polymorphisms with Cis-Regulatory Effects on Long Non-Coding Transcripts in Human Primary Monocytes

Jonas Carlsson Almlöf,

Affiliation Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala University, Uppsala, Sweden
⨯
Per Lundmark,

Affiliation Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala University, Uppsala, Sweden
⨯
Anders Lundmark,

Affiliation Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala University, Uppsala, Sweden
⨯
Bing Ge,

Affiliation Department of Human Genetics, McGill University, Montréal, Canada
⨯
Tomi Pastinen,

Affiliation Department of Human Genetics, McGill University, Montréal, Canada
⨯
Cardiogenics Consortium ,

¶Members of the CARDIOGENICS Consortium are listed in the Acknowledgements.
⨯
Alison H. Goodall,

Affiliations Department of Cardiovascular Science, University of Leicester, Leicester, United Kingdom, Leicester NIHR Biomedical Research Unit in Cardiovascular Disease, Glenfield Hospital, Leicester, United Kingdom
⨯
François Cambien,

Affiliation INSERM UMRS 937, Pierre and Marie Curie University and Medical School, Paris, France
⨯
Panos Deloukas,

Affiliations William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Heart Centre, Charterhouse Square London, United Kingdom, Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom, Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia
⨯
Willem H. Ouwehand,

Affiliations Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom, National Health Service Blood and Transplant, Cambridge Centre, Long Road, Cambridge, United Kingdom
⨯
Ann-Christine Syvänen

* E-mail: Ann-Christine.Syvanen@medsci.uu.se

Affiliation Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala University, Uppsala, Sweden
⨯

Single Nucleotide Polymorphisms with Cis-Regulatory Effects on Long Non-Coding Transcripts in Human Primary Monocytes

Jonas Carlsson Almlöf,
Per Lundmark,
Anders Lundmark,
Bing Ge,
Tomi Pastinen,
Cardiogenics Consortium,
Alison H. Goodall,
François Cambien,
Panos Deloukas,
Willem H. Ouwehand

Published: July 15, 2014
https://doi.org/10.1371/journal.pone.0102612

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Long non-coding RNA
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Single nucleotide polymorphisms
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Genome-wide association studies
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Gene expression
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Monocytes
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Gene regulation
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Genomics
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Heterozygosity
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