Characterization of Subtle Brain Abnormalities in a Mouse Model of Hedgehog Pathway Antagonist-Induced Cleft Lip and Palate

Robert J. Lipinski; Hunter T. Holloway; Shonagh K. O'Leary-Moore; Jacob J. Ament; Stephen J. Pecevich; Gary P. Cofer; Francois Budin; Joshua L. Everson; G. Allan Johnson; Kathleen K. Sulik

doi:10.1371/journal.pone.0102603

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Peer-reviewed

Research Article

Characterization of Subtle Brain Abnormalities in a Mouse Model of Hedgehog Pathway Antagonist-Induced Cleft Lip and Palate

Robert J. Lipinski ,

* E-mail: rjlipinski@wisc.edu

Affiliations The Bowles Center for Alcohol Studies, University of North Carolina, Chapel Hill, North Carolina, United States of America, Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
⨯
Hunter T. Holloway,

Affiliation The Bowles Center for Alcohol Studies, University of North Carolina, Chapel Hill, North Carolina, United States of America
⨯
Shonagh K. O'Leary-Moore,

Affiliations The Bowles Center for Alcohol Studies, University of North Carolina, Chapel Hill, North Carolina, United States of America, Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, United States of America
⨯
Jacob J. Ament,

Affiliation The Bowles Center for Alcohol Studies, University of North Carolina, Chapel Hill, North Carolina, United States of America
⨯
Stephen J. Pecevich,

Affiliation The Bowles Center for Alcohol Studies, University of North Carolina, Chapel Hill, North Carolina, United States of America
⨯
Gary P. Cofer,

Affiliation Center for In Vivo Microscopy, Duke University, Durham, North Carolina, United States of America
⨯
Francois Budin,

Affiliation Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, United States of America
⨯
Joshua L. Everson,

Affiliation Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
⨯
G. Allan Johnson,

Affiliation Center for In Vivo Microscopy, Duke University, Durham, North Carolina, United States of America
⨯
Kathleen K. Sulik

Affiliations The Bowles Center for Alcohol Studies, University of North Carolina, Chapel Hill, North Carolina, United States of America, Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, North Carolina, United States of America
⨯

Characterization of Subtle Brain Abnormalities in a Mouse Model of Hedgehog Pathway Antagonist-Induced Cleft Lip and Palate

Robert J. Lipinski,
Hunter T. Holloway,
Shonagh K. O'Leary-Moore,
Jacob J. Ament,
Stephen J. Pecevich,
Gary P. Cofer,
Francois Budin,
Joshua L. Everson,
G. Allan Johnson,
Kathleen K. Sulik

Published: July 21, 2014
https://doi.org/10.1371/journal.pone.0102603

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Hedgehog signaling
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