Tetrandrine Suppresses Lipopolysaccharide-Induced Microglial Activation by Inhibiting NF-κB and ERK Signaling Pathways in BV2 Cells

Yalong Dang; Yongsheng Xu; Wentao Wu; Weiyi Li; Yanran Sun; Jing Yang; Yu Zhu; Chun Zhang

doi:10.1371/journal.pone.0102522

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Peer-reviewed

Research Article

Tetrandrine Suppresses Lipopolysaccharide-Induced Microglial Activation by Inhibiting NF-κB and ERK Signaling Pathways in BV2 Cells

Yalong Dang,

Affiliations Department of Ophthalmology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou City, Henan Province, People's Republic of China, Clinical Stem Cell Research Center, Peking University Third Hospital, Beijing, People's Republic of China, Department of Ophthalmology, Peking University Third Hospital, Beijing, People's Republic of China
⨯
Yongsheng Xu,

Affiliations Clinical Stem Cell Research Center, Peking University Third Hospital, Beijing, People's Republic of China, Department of Ophthalmology, Peking University Third Hospital, Beijing, People's Republic of China
⨯
Wentao Wu,

Affiliation Clinical Stem Cell Research Center, Peking University Third Hospital, Beijing, People's Republic of China
⨯
Weiyi Li,

Affiliations Clinical Stem Cell Research Center, Peking University Third Hospital, Beijing, People's Republic of China, Department of Ophthalmology, Peking University Third Hospital, Beijing, People's Republic of China
⨯
Yanran Sun,

Affiliation Department of Ophthalmology, Peking University Third Hospital, Beijing, People's Republic of China
⨯
Jing Yang,

Affiliation Department of Ophthalmology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou City, Henan Province, People's Republic of China
⨯
Yu Zhu ,

* E-mail: asiadragon@163.com (YZ); zhangc1@yahoo.com (CZ)

Affiliation Department of Ophthalmology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou City, Henan Province, People's Republic of China
⨯
Chun Zhang

* E-mail: asiadragon@163.com (YZ); zhangc1@yahoo.com (CZ)

Affiliations Clinical Stem Cell Research Center, Peking University Third Hospital, Beijing, People's Republic of China, Department of Ophthalmology, Peking University Third Hospital, Beijing, People's Republic of China
⨯

Tetrandrine Suppresses Lipopolysaccharide-Induced Microglial Activation by Inhibiting NF-κB and ERK Signaling Pathways in BV2 Cells

Yalong Dang,
Yongsheng Xu,
Wentao Wu,
Weiyi Li,
Yanran Sun,
Jing Yang,
Yu Zhu,
Chun Zhang

Published: August 12, 2014
https://doi.org/10.1371/journal.pone.0102522

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