Comparative 2D-DIGE Proteomic Analysis of Bovine Mammary Epithelial Cells during Lactation Reveals Protein Signatures for Lactation Persistency and Milk Yield

Jagadeesh Janjanam; Surender Singh; Manoj K. Jena; Nishant Varshney; Srujana Kola; Sudarshan Kumar; Jai K. Kaushik; Sunita Grover; Ajay K. Dang; Manishi Mukesh; B. S. Prakash; Ashok K. Mohanty

doi:10.1371/journal.pone.0102515

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Open Access

Peer-reviewed

Research Article

Comparative 2D-DIGE Proteomic Analysis of Bovine Mammary Epithelial Cells during Lactation Reveals Protein Signatures for Lactation Persistency and Milk Yield

Jagadeesh Janjanam ,

* E-mail: ashokmohanty1@gmail.com (JJ); jjanjana@uthsc.edu (AKM)

Current address: Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America

Affiliation Animal Biotechnology Center, National Dairy Research Institute, Karnal, India
⨯
Surender Singh,

Affiliation Animal Biotechnology Center, National Dairy Research Institute, Karnal, India
⨯
Manoj K. Jena,

Affiliation Animal Biotechnology Center, National Dairy Research Institute, Karnal, India
⨯
Nishant Varshney,

Affiliation Animal Biotechnology Center, National Dairy Research Institute, Karnal, India
⨯
Srujana Kola,

Affiliation Department of Biophysics, All India Institute of Medical Sciences, New Delhi, India
⨯
Sudarshan Kumar,

Affiliation Animal Biotechnology Center, National Dairy Research Institute, Karnal, India
⨯
Jai K. Kaushik,

Affiliation Animal Biotechnology Center, National Dairy Research Institute, Karnal, India
⨯
Sunita Grover,

Affiliation Animal Biotechnology Center, National Dairy Research Institute, Karnal, India
⨯
Ajay K. Dang,

Affiliation Dairy Cattle Physiology Division, National Dairy Research Institute, Karnal, India
⨯
Manishi Mukesh,

Affiliation National Bureau of Animal Genetic Resources, Karnal, India
⨯
B. S. Prakash,

Affiliation Dairy Cattle Physiology Division, National Dairy Research Institute, Karnal, India
⨯
Ashok K. Mohanty

* E-mail: ashokmohanty1@gmail.com (JJ); jjanjana@uthsc.edu (AKM)

Affiliation Animal Biotechnology Center, National Dairy Research Institute, Karnal, India
⨯

Comparative 2D-DIGE Proteomic Analysis of Bovine Mammary Epithelial Cells during Lactation Reveals Protein Signatures for Lactation Persistency and Milk Yield

Jagadeesh Janjanam,
Surender Singh,
Manoj K. Jena,
Nishant Varshney,
Srujana Kola,
Sudarshan Kumar,
Jai K. Kaushik,
Sunita Grover,
Ajay K. Dang,
Manishi Mukesh

Published: August 11, 2014
https://doi.org/10.1371/journal.pone.0102515

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Lactation
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Milk
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Cytoskeletal proteins
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Protein expression
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Transcription factors
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Epithelial cells
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Principal component analysis
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Cytoskeleton
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