Phage Orf Family Recombinases: Conservation of Activities and Involvement of the Central Channel in DNA Binding

Fiona A. Curtis; Ali D. Malay; Alexander J. Trotter; Lindsay A. Wilson; Michael M. H. Barradell-Black; Laura Y. Bowers; Patricia Reed; Christopher R. T. Hillyar; Robert P. Yeo; John M. Sanderson; Jonathan G. Heddle; Gary J. Sharples

doi:10.1371/journal.pone.0102454

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Open Access

Peer-reviewed

Research Article

Phage Orf Family Recombinases: Conservation of Activities and Involvement of the Central Channel in DNA Binding

Fiona A. Curtis,

Affiliation School of Biological and Biomedical Sciences, Biophysical Sciences Institute, Durham University, Durham, United Kingdom
⨯
Ali D. Malay,

Affiliation Heddle Initiative Research Unit, RIKEN, Wako, Saitama, Japan
⨯
Alexander J. Trotter,

Affiliation School of Biological and Biomedical Sciences, Biophysical Sciences Institute, Durham University, Durham, United Kingdom
⨯
Lindsay A. Wilson,

Affiliation School of Biological and Biomedical Sciences, Biophysical Sciences Institute, Durham University, Durham, United Kingdom
⨯
Michael M. H. Barradell-Black,

Affiliation School of Biological and Biomedical Sciences, Biophysical Sciences Institute, Durham University, Durham, United Kingdom
⨯
Laura Y. Bowers,

Affiliation School of Biological and Biomedical Sciences, Biophysical Sciences Institute, Durham University, Durham, United Kingdom
⨯
Patricia Reed,

Affiliation School of Biological and Biomedical Sciences, Biophysical Sciences Institute, Durham University, Durham, United Kingdom
⨯
Christopher R. T. Hillyar,

Affiliation School of Biological and Biomedical Sciences, Biophysical Sciences Institute, Durham University, Durham, United Kingdom
⨯
Robert P. Yeo,

Affiliation School of Biological and Biomedical Sciences, Biophysical Sciences Institute, Durham University, Durham, United Kingdom
⨯
John M. Sanderson,

Affiliation Department of Chemistry, Biophysical Sciences Institute, Durham University, Durham, United Kingdom
⨯
Jonathan G. Heddle,

Affiliation Heddle Initiative Research Unit, RIKEN, Wako, Saitama, Japan
⨯
Gary J. Sharples

* E-mail: gary.sharples@durham.ac.uk

Affiliation School of Biological and Biomedical Sciences, Biophysical Sciences Institute, Durham University, Durham, United Kingdom
⨯

Phage Orf Family Recombinases: Conservation of Activities and Involvement of the Central Channel in DNA Binding

Fiona A. Curtis,
Ali D. Malay,
Alexander J. Trotter,
Lindsay A. Wilson,
Michael M. H. Barradell-Black,
Laura Y. Bowers,
Patricia Reed,
Christopher R. T. Hillyar,
Robert P. Yeo,
John M. Sanderson

Published: August 1, 2014
https://doi.org/10.1371/journal.pone.0102454

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DNA-binding proteins
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Bacteriophages
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Gene prediction
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DNA recombination
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DNA binding assay
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DNA annealing
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Anisotropy
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Protein structure prediction
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