Correlation between In Vitro Cytotoxicity and In Vivo Lethal Activity in Mice of Epsilon Toxin Mutants from Clostridium perfringens

• Jonatan Dorca-Arévalo,

  Affiliations Laboratory of Cellular and Molecular Neuroscience, Department of Pathology and Experimental Therapeutics, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain, IDIBELL-Bellvitge Biomedical Research Institute, L'Hospitalet de Llobregat, Barcelona, Spain

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• Serge Pauillac,

  Affiliation Institut Pasteur, Unité des Bactéries anaérobies et Toxines, Paris, France

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• Laura Díaz-Hidalgo,

  Current address: Department of Biology, University of Rome “Tor Vergata”, Rome, Italy

  Affiliation Laboratory of Cellular and Molecular Neuroscience, Department of Pathology and Experimental Therapeutics, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain

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• Mireia Martín-Satué,

  Affiliations Laboratory of Cellular and Molecular Neuroscience, Department of Pathology and Experimental Therapeutics, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain, IDIBELL-Bellvitge Biomedical Research Institute, L'Hospitalet de Llobregat, Barcelona, Spain

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• Michel R. Popoff,

  Affiliation Institut Pasteur, Unité des Bactéries anaérobies et Toxines, Paris, France

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• Juan Blasi

  * E-mail: blasi@ub.edu

  Affiliations Laboratory of Cellular and Molecular Neuroscience, Department of Pathology and Experimental Therapeutics, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain, IDIBELL-Bellvitge Biomedical Research Institute, L'Hospitalet de Llobregat, Barcelona, Spain

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