Surfactant Protein D Inhibits HIV-1 Infection of Target Cells via Interference with gp120-CD4 Interaction and Modulates Pro-Inflammatory Cytokine Production

Hrishikesh Pandit; Sandhya Gopal; Archana Sonawani; Ajit Kumar Yadav; Asif S. Qaseem; Himangi Warke; Anushree Patil; Rahul Gajbhiye; Vijay Kulkarni; Maha Ahmed Al-Mozaini; Susan Idicula-Thomas; Uday Kishore; Taruna Madan

doi:10.1371/journal.pone.0102395

Loading metrics

Open Access

Peer-reviewed

Research Article

Surfactant Protein D Inhibits HIV-1 Infection of Target Cells via Interference with gp120-CD4 Interaction and Modulates Pro-Inflammatory Cytokine Production

Hrishikesh Pandit,

Affiliation Department of Innate Immunity, National Institute for Research in Reproductive Health (ICMR), Mumbai, Maharashtra, India
⨯
Sandhya Gopal,

Current address: Department of Molecular Biosciences, University of Texas, Austin, Austin, Texas, United States of America

Affiliation Department of Innate Immunity, National Institute for Research in Reproductive Health (ICMR), Mumbai, Maharashtra, India
⨯
Archana Sonawani,

Affiliation Biomedical Informatics Centre, National Institute for Research in Reproductive Health (ICMR), Mumbai, Maharashtra, India
⨯
Ajit Kumar Yadav,

Affiliation Department of Innate Immunity, National Institute for Research in Reproductive Health (ICMR), Mumbai, Maharashtra, India
⨯
Asif S. Qaseem,

Affiliation Centre for Infection, Immunity and Disease Mechanisms, Brunel University, London, United Kingdom
⨯
Himangi Warke,

Affiliation Department of Obstetrics and Gynecology, Seth G S Medical College and K E M Hospital, Mumbai, Maharashtra, India
⨯
Anushree Patil,

Affiliation Department of Clinical Research, National Institute for Research in Reproductive Health (ICMR), Mumbai, Maharashtra, India
⨯
Rahul Gajbhiye,

Affiliation Department of Clinical Research, National Institute for Research in Reproductive Health (ICMR), Mumbai, Maharashtra, India
⨯
Vijay Kulkarni,

Affiliation Department of Clinical Research, National Institute for Research in Reproductive Health (ICMR), Mumbai, Maharashtra, India
⨯
Maha Ahmed Al-Mozaini,

Affiliation Immunocompromised Host Research Section, Department of Infection and Immunity, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
⨯
Susan Idicula-Thomas,

Affiliation Biomedical Informatics Centre, National Institute for Research in Reproductive Health (ICMR), Mumbai, Maharashtra, India
⨯
Uday Kishore,

Affiliation Centre for Infection, Immunity and Disease Mechanisms, Brunel University, London, United Kingdom
⨯
Taruna Madan

* E-mail: taruna_m@hotmail.com

Affiliation Department of Innate Immunity, National Institute for Research in Reproductive Health (ICMR), Mumbai, Maharashtra, India
⨯

Surfactant Protein D Inhibits HIV-1 Infection of Target Cells via Interference with gp120-CD4 Interaction and Modulates Pro-Inflammatory Cytokine Production

Hrishikesh Pandit,
Sandhya Gopal,
Archana Sonawani,
Ajit Kumar Yadav,
Asif S. Qaseem,
Himangi Warke,
Anushree Patil,
Rahul Gajbhiye,
Vijay Kulkarni,
Maha Ahmed Al-Mozaini

Published: July 18, 2014
https://doi.org/10.1371/journal.pone.0102395

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

HIV-1
Is the Subject Area "HIV-1" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
HIV
Is the Subject Area "HIV" applicable to this article?

Thanks for your feedback.
HIV infections
Is the Subject Area "HIV infections" applicable to this article?

Thanks for your feedback.
Monocytes
Is the Subject Area "Monocytes" applicable to this article?

Thanks for your feedback.
Cytokine therapy
Is the Subject Area "Cytokine therapy" applicable to this article?

Thanks for your feedback.
Viral replication
Is the Subject Area "Viral replication" applicable to this article?

Thanks for your feedback.