Differences in TCR-Vβ Repertoire and Effector Phenotype between Tumor Infiltrating Lymphocytes and Peripheral Blood Lymphocytes Increase with Age

Hongwei Shao; Yusheng Ou; Teng Wang; Han Shen; Fenglin Wu; Wenfeng Zhang; Changli Tao; Yin Yuan; Huaben Bo; Hui Wang; Shulin Huang

doi:10.1371/journal.pone.0102327

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Peer-reviewed

Research Article

Differences in TCR-Vβ Repertoire and Effector Phenotype between Tumor Infiltrating Lymphocytes and Peripheral Blood Lymphocytes Increase with Age

Hongwei Shao ,

Contributed equally to this work with: Hongwei Shao, Yusheng Ou

Affiliations Guangdong Province Key Laboratory for Biotechnology Drug Candidates, Guangzhou, China, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China
⨯
Yusheng Ou ,

Contributed equally to this work with: Hongwei Shao, Yusheng Ou

Affiliations Guangdong Province Key Laboratory for Biotechnology Drug Candidates, Guangzhou, China, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China
⨯
Teng Wang,

Affiliations Guangdong Province Key Laboratory for Biotechnology Drug Candidates, Guangzhou, China, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China
⨯
Han Shen,

Affiliations Guangdong Province Key Laboratory for Biotechnology Drug Candidates, Guangzhou, China, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China
⨯
Fenglin Wu,

Affiliations Guangdong Province Key Laboratory for Biotechnology Drug Candidates, Guangzhou, China, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China
⨯
Wenfeng Zhang,

Affiliations Guangdong Province Key Laboratory for Biotechnology Drug Candidates, Guangzhou, China, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China
⨯
Changli Tao,

Affiliations Guangdong Province Key Laboratory for Biotechnology Drug Candidates, Guangzhou, China, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China
⨯
Yin Yuan,

Affiliations Guangdong Province Key Laboratory for Biotechnology Drug Candidates, Guangzhou, China, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China
⨯
Huaben Bo,

Affiliations Guangdong Province Key Laboratory for Biotechnology Drug Candidates, Guangzhou, China, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China
⨯
Hui Wang,

Affiliations Guangdong Province Key Laboratory for Biotechnology Drug Candidates, Guangzhou, China, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China
⨯
Shulin Huang

* E-mail: shulhuang@sina.com

Affiliations Guangdong Province Key Laboratory for Biotechnology Drug Candidates, Guangzhou, China, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China, Southern Medical University, Guangzhou, China
⨯

Differences in TCR-Vβ Repertoire and Effector Phenotype between Tumor Infiltrating Lymphocytes and Peripheral Blood Lymphocytes Increase with Age

Hongwei Shao,
Yusheng Ou,
Teng Wang,
Han Shen,
Fenglin Wu,
Wenfeng Zhang,
Changli Tao,
Yin Yuan,
Huaben Bo,
Hui Wang

Published: July 14, 2014
https://doi.org/10.1371/journal.pone.0102327

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