Neutrophils Contribute to Excess Serum BAFF Levels and Promote CD4+ T Cell and B Cell Responses in Lupus-Prone Mice

Christine M. Coquery; Nekeithia S. Wade; William M. Loo; Jason M. Kinchen; Kelly M. Cox; Chao Jiang; Kenneth S. Tung; Loren D. Erickson

doi:10.1371/journal.pone.0102284

Loading metrics

Open Access

Peer-reviewed

Research Article

Neutrophils Contribute to Excess Serum BAFF Levels and Promote CD4⁺ T Cell and B Cell Responses in Lupus-Prone Mice

Christine M. Coquery,

Affiliations Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia, United States of America, Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, Virginia, United States of America
⨯
Nekeithia S. Wade,

Affiliation Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, Virginia, United States of America
⨯
William M. Loo,

Affiliation Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, Virginia, United States of America
⨯
Jason M. Kinchen,

Affiliations Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia, United States of America, Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, Virginia, United States of America, Center for Cell Clearance, University of Virginia, Charlottesville, Virginia, United States of America
⨯
Kelly M. Cox,

Affiliations Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia, United States of America, Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, Virginia, United States of America
⨯
Chao Jiang,

Affiliation Division of Extramural Research, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Kenneth S. Tung,

Affiliations Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, Virginia, United States of America, Department of Pathology, University of Virginia, Charlottesville, Virginia, United States of America
⨯
Loren D. Erickson

* E-mail: lde9w@virginia.edu

Affiliations Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia, United States of America, Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, Virginia, United States of America
⨯

Neutrophils Contribute to Excess Serum BAFF Levels and Promote CD4⁺ T Cell and B Cell Responses in Lupus-Prone Mice

Christine M. Coquery,
Nekeithia S. Wade,
William M. Loo,
Jason M. Kinchen,
Kelly M. Cox,
Chao Jiang,
Kenneth S. Tung,
Loren D. Erickson

Published: July 10, 2014
https://doi.org/10.1371/journal.pone.0102284

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Neutrophils
Is the Subject Area "Neutrophils" applicable to this article?

Thanks for your feedback.
T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
Spleen
Is the Subject Area "Spleen" applicable to this article?

Thanks for your feedback.
B cells
Is the Subject Area "B cells" applicable to this article?

Thanks for your feedback.
Autoantibodies
Is the Subject Area "Autoantibodies" applicable to this article?

Thanks for your feedback.
Autoimmunity
Is the Subject Area "Autoimmunity" applicable to this article?

Thanks for your feedback.
Systemic lupus erythematosus
Is the Subject Area "Systemic lupus erythematosus" applicable to this article?

Thanks for your feedback.
Flow cytometry
Is the Subject Area "Flow cytometry" applicable to this article?

Thanks for your feedback.