A Preliminary Study of the Relationship between Promoter Methylation of the ABCG1, GALNT2 and HMGCR Genes and Coronary Heart Disease

Ping Peng; Lu Wang; Xi Yang; Xiaoyan Huang; Yanna Ba; Xiaoliang Chen; Jian Guo; Jiangfang Lian; Jianqing Zhou

doi:10.1371/journal.pone.0102265

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Open Access

Peer-reviewed

Research Article

A Preliminary Study of the Relationship between Promoter Methylation of the ABCG1, GALNT2 and HMGCR Genes and Coronary Heart Disease

Ping Peng ,

¶PP and LW are joint senior authors on this work.

Affiliations Ningbo Medical Center, Lihuili Hospital, Ningbo University, Ningbo, Zhejiang, China, The Affiliated Hospital, School of Medicine, Ningbo University, Ningbo, Zhejiang, China
⨯
Lu Wang ,

¶PP and LW are joint senior authors on this work.

Affiliation School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom
⨯
Xi Yang,

Affiliation Ningbo Medical Center, Lihuili Hospital, Ningbo University, Ningbo, Zhejiang, China
⨯
Xiaoyan Huang,

Affiliation Ningbo Medical Center, Lihuili Hospital, Ningbo University, Ningbo, Zhejiang, China
⨯
Yanna Ba,

Affiliations Ningbo Medical Center, Lihuili Hospital, Ningbo University, Ningbo, Zhejiang, China, The Affiliated Hospital, School of Medicine, Ningbo University, Ningbo, Zhejiang, China
⨯
Xiaoliang Chen,

Affiliations Ningbo Medical Center, Lihuili Hospital, Ningbo University, Ningbo, Zhejiang, China, The Affiliated Hospital, School of Medicine, Ningbo University, Ningbo, Zhejiang, China
⨯
Jian Guo,

Affiliations Ningbo Medical Center, Lihuili Hospital, Ningbo University, Ningbo, Zhejiang, China, The Affiliated Hospital, School of Medicine, Ningbo University, Ningbo, Zhejiang, China
⨯
Jiangfang Lian ,

* E-mail: hjmpin@163.com (JL); pengpingnb@163.com (JZ)

Affiliation Ningbo Medical Center, Lihuili Hospital, Ningbo University, Ningbo, Zhejiang, China
⨯
Jianqing Zhou

* E-mail: hjmpin@163.com (JL); pengpingnb@163.com (JZ)

Affiliation Ningbo Medical Center, Lihuili Hospital, Ningbo University, Ningbo, Zhejiang, China
⨯

A Preliminary Study of the Relationship between Promoter Methylation of the ABCG1, GALNT2 and HMGCR Genes and Coronary Heart Disease

Ping Peng,
Lu Wang,
Xi Yang,
Xiaoyan Huang,
Yanna Ba,
Xiaoliang Chen,
Jian Guo,
Jiangfang Lian,
Jianqing Zhou

Published: August 1, 2014
https://doi.org/10.1371/journal.pone.0102265

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DNA methylation
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Methylation
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Coronary heart disease
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Cardiovascular disease risk
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Cholesterol
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Promoter regions
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Lipids
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