The Spleen Responds to Intestinal Manipulation but Does Not Participate in the Inflammatory Response in a Mouse Model of Postoperative Ileus

Léa M. M. Costes; Jan van der Vliet; Giovanna Farro; Gianluca Matteoli; Sjoerd H. W. van Bree; Brenda J. Olivier; Martijn A. Nolte; Guy E. Boeckxstaens; Cathy Cailotto

doi:10.1371/journal.pone.0102211

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Peer-reviewed

Research Article

The Spleen Responds to Intestinal Manipulation but Does Not Participate in the Inflammatory Response in a Mouse Model of Postoperative Ileus

Léa M. M. Costes ,

* E-mail: l.m.costes@amc.nl

Affiliation Tytgat Institute for Liver and Intestinal Research, Academic medical center (AMC), Amsterdam, The Netherlands
⨯
Jan van der Vliet,

Affiliation Tytgat Institute for Liver and Intestinal Research, Academic medical center (AMC), Amsterdam, The Netherlands
⨯
Giovanna Farro,

Affiliation Department of Clinical and Experimental Medicine, Translational Research Center for Gastrointestinal Disorders (TARGID), KU Leuven, Belgium
⨯
Gianluca Matteoli,

Affiliation Department of Clinical and Experimental Medicine, Translational Research Center for Gastrointestinal Disorders (TARGID), KU Leuven, Belgium
⨯
Sjoerd H. W. van Bree,

Affiliation Tytgat Institute for Liver and Intestinal Research, Academic medical center (AMC), Amsterdam, The Netherlands
⨯
Brenda J. Olivier,

Affiliations Tytgat Institute for Liver and Intestinal Research, Academic medical center (AMC), Amsterdam, The Netherlands, Adaptive Immunity Lab, Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory AMC/UvA, Amsterdam, The Netherlands
⨯
Martijn A. Nolte,

Affiliation Adaptive Immunity Lab, Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory AMC/UvA, Amsterdam, The Netherlands
⨯
Guy E. Boeckxstaens,

Affiliation Department of Clinical and Experimental Medicine, Translational Research Center for Gastrointestinal Disorders (TARGID), KU Leuven, Belgium
⨯
Cathy Cailotto

Affiliation Tytgat Institute for Liver and Intestinal Research, Academic medical center (AMC), Amsterdam, The Netherlands
⨯

The Spleen Responds to Intestinal Manipulation but Does Not Participate in the Inflammatory Response in a Mouse Model of Postoperative Ileus

Léa M. M. Costes,
Jan van der Vliet,
Giovanna Farro,
Gianluca Matteoli,
Sjoerd H. W. van Bree,
Brenda J. Olivier,
Martijn A. Nolte,
Guy E. Boeckxstaens,
Cathy Cailotto

Published: July 10, 2014
https://doi.org/10.1371/journal.pone.0102211

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Gastrointestinal tract
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Spleen
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Colon
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Monocytes
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Small intestine
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