Pancreatic Insulin-Producing Cells Differentiated from Human Embryonic Stem Cells Correct Hyperglycemia in SCID/NOD Mice, an Animal Model of Diabetes

Xiu-feng Hua; Yan-wei Wang; Yu-xiao Tang; Sheng-qiang Yu; Shao-hua Jin; Xiao-mei Meng; Hua-feng Li; Fu-jun Liu; Qiang Sun; Hai-yan Wang; Jian-yuan Li

doi:10.1371/journal.pone.0102198

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Open Access

Peer-reviewed

Research Article

Pancreatic Insulin-Producing Cells Differentiated from Human Embryonic Stem Cells Correct Hyperglycemia in SCID/NOD Mice, an Animal Model of Diabetes

Xiu-feng Hua ,

Contributed equally to this work with: Xiu-feng Hua, Yan-wei Wang

Affiliation Department of Endocrinology, Yuhuangding Hospital, Yantai, Shandong Province, China
⨯
Yan-wei Wang ,

Contributed equally to this work with: Xiu-feng Hua, Yan-wei Wang

Affiliation Research Center of Stem Cell Engineering of Shandong, Central Laboratory of Yuhuangding Hospital, Yantai, Shandong Province, China
⨯
Yu-xiao Tang,

Affiliation Department of Endocrinology, Yuhuangding Hospital, Yantai, Shandong Province, China
⨯
Sheng-qiang Yu,

Affiliation Department of Urology, Yuhuangding Hospital, Yantai, Shandong Province, China
⨯
Shao-hua Jin,

Affiliation Department of clinical laboratory, Yuhuangding Hospital, Yantai, Shangdong Province, China
⨯
Xiao-mei Meng,

Affiliation Department of Endocrinology, Yuhuangding Hospital, Yantai, Shandong Province, China
⨯
Hua-feng Li,

Affiliation Department of Endocrinology, Yuhuangding Hospital, Yantai, Shandong Province, China
⨯
Fu-jun Liu,

Affiliation Research Center of Stem Cell Engineering of Shandong, Central Laboratory of Yuhuangding Hospital, Yantai, Shandong Province, China
⨯
Qiang Sun,

Affiliation Department of Orthopedics, Chinese people's Liberation Army Navy 407 hospital, Yantai, Shandong Province, China
⨯
Hai-yan Wang,

Affiliation Research Center of Stem Cell Engineering of Shandong, Central Laboratory of Yuhuangding Hospital, Yantai, Shandong Province, China
⨯
Jian-yuan Li

* E-mail: sdscli@yeah.net

Affiliation Research Center of Stem Cell Engineering of Shandong, Central Laboratory of Yuhuangding Hospital, Yantai, Shandong Province, China
⨯

Pancreatic Insulin-Producing Cells Differentiated from Human Embryonic Stem Cells Correct Hyperglycemia in SCID/NOD Mice, an Animal Model of Diabetes

Xiu-feng Hua,
Yan-wei Wang,
Yu-xiao Tang,
Sheng-qiang Yu,
Shao-hua Jin,
Xiao-mei Meng,
Hua-feng Li,
Fu-jun Liu,
Qiang Sun,
Hai-yan Wang

Published: July 10, 2014
https://doi.org/10.1371/journal.pone.0102198

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