Anti-Epileptic Effect of Ganoderma Lucidum Polysaccharides by Inhibition of Intracellular Calcium Accumulation and Stimulation of Expression of CaMKII α in Epileptic Hippocampal Neurons

Shu-Qiu Wang; Xiao-Jie Li; Hong-Bin Qiu; Zhi-Mei Jiang; Maria Simon; Xiao-Ru Ma; Lei Liu; Jun-Xing Liu; Fang-Fang Wang; Yan-Feng Liang; Jia-Mei Wu; Wei-Hua Di; Shaobo Zhou

doi:10.1371/journal.pone.0102161

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Open Access

Peer-reviewed

Research Article

Anti-Epileptic Effect of Ganoderma Lucidum Polysaccharides by Inhibition of Intracellular Calcium Accumulation and Stimulation of Expression of CaMKII α in Epileptic Hippocampal Neurons

Shu-Qiu Wang ,

* E-mail: wangshuq_jms@163.com

Affiliation Department of Pathophysiology, School of Basic Medical Sciences, Jiamusi University, Jiamusi, P. R. China
⨯
Xiao-Jie Li,

Affiliation Children Neural Rehabilitation Laboratory of Jiamusi University, School of Rehabilitation Medical Sciences, Jiamusi University, Jiamusi, Heilongjiang Province, P. R. China
⨯
Hong-Bin Qiu,

Affiliation School of Public Health, Jiamusi University, Jiamusi, Heilongiang Province, P.R. China
⨯
Zhi-Mei Jiang,

Affiliation Children Neural Rehabilitation Laboratory of Jiamusi University, School of Rehabilitation Medical Sciences, Jiamusi University, Jiamusi, Heilongjiang Province, P. R. China
⨯
Maria Simon,

Affiliation Department of Life Science, Institute of Biomedical and Environmental Science and Technology, University of Bedfordshire, Luton, United Kingdom
⨯
Xiao-Ru Ma,

Affiliation Department of Pathophysiology, School of Basic Medical Sciences, Jiamusi University, Jiamusi, P. R. China
⨯
Lei Liu,

Affiliation Department of Pathophysiology, School of Basic Medical Sciences, Jiamusi University, Jiamusi, P. R. China
⨯
Jun-Xing Liu,

Affiliation Department of Pathophysiology, School of Basic Medical Sciences, Jiamusi University, Jiamusi, P. R. China
⨯
Fang-Fang Wang,

Affiliation Department of Pathophysiology, School of Basic Medical Sciences, Jiamusi University, Jiamusi, P. R. China
⨯
Yan-Feng Liang,

Affiliation Department of Pathophysiology, School of Basic Medical Sciences, Jiamusi University, Jiamusi, P. R. China
⨯
Jia-Mei Wu,

Affiliation Department of Pathophysiology, School of Basic Medical Sciences, Jiamusi University, Jiamusi, P. R. China
⨯
Wei-Hua Di,

Affiliation Department of Pathophysiology, School of Basic Medical Sciences, Jiamusi University, Jiamusi, P. R. China
⨯
Shaobo Zhou

Affiliations Department of Pathophysiology, School of Basic Medical Sciences, Jiamusi University, Jiamusi, P. R. China, Department of Life Science, Institute of Biomedical and Environmental Science and Technology, University of Bedfordshire, Luton, United Kingdom
⨯

Anti-Epileptic Effect of Ganoderma Lucidum Polysaccharides by Inhibition of Intracellular Calcium Accumulation and Stimulation of Expression of CaMKII α in Epileptic Hippocampal Neurons

Shu-Qiu Wang,
Xiao-Jie Li,
Hong-Bin Qiu,
Zhi-Mei Jiang,
Maria Simon,
Xiao-Ru Ma,
Lei Liu,
Jun-Xing Liu,
Fang-Fang Wang,
Yan-Feng Liang

Published: July 10, 2014
https://doi.org/10.1371/journal.pone.0102161

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