Disruption of Ion-Trafficking System in the Cochlear Spiral Ligament Prior to Permanent Hearing Loss Induced by Exposure to Intense Noise: Possible Involvement of 4-Hydroxy-2-Nonenal as a Mediator of Oxidative Stress

Open Access

Peer-reviewed

Research Article

Taro Yamaguchi,

Affiliation Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan
⨯
Reiko Nagashima,

Affiliation Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan
⨯
Masanori Yoneyama,

Affiliation Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan
⨯
Tatsuo Shiba,

Affiliation Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan
⨯
Kiyokazu Ogita

* E-mail: ogita@pharm.setsunan.ac.jp

Affiliation Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan
⨯

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Deafness
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Cochlea
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Immunoblot analysis
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Oxidative stress
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Acoustics
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Immunostaining
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Basal cells
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Nitric oxide
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