Inhibition of Angiotensin II-Induced Cardiac Hypertrophy and Associated Ventricular Arrhythmias by a p21 Activated Kinase 1 Bioactive Peptide

• Rui Wang ,

  Contributed equally to this work with: Rui Wang, Yanwen Wang

  ¶These authors are joint first authors on this work.

  Affiliation Institute for Cardiovascular Diseases, Union Hospital, Huazhong University of Science and Technology, Wuhan, P. R. China

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• Yanwen Wang ,

  Contributed equally to this work with: Rui Wang, Yanwen Wang

  Affiliations Institute of Cardiovascular Sciences, Faculty of Medicine and Human Science, University of Manchester, Manchester, United Kingdom, Department of Pharmacology, University of Oxford, Oxford, United Kingdom

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• Wee K. Lin,

  Affiliation Department of Pharmacology, University of Oxford, Oxford, United Kingdom

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• Yanmin Zhang,

  Affiliation Institute of Cardiovascular Sciences, Faculty of Medicine and Human Science, University of Manchester, Manchester, United Kingdom

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• Wei Liu,

  Affiliation Institute of Cardiovascular Sciences, Faculty of Medicine and Human Science, University of Manchester, Manchester, United Kingdom

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• Kai Huang,

  Affiliation Institute for Cardiovascular Diseases, Union Hospital, Huazhong University of Science and Technology, Wuhan, P. R. China

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• Derek A. Terrar,

  Affiliation Department of Pharmacology, University of Oxford, Oxford, United Kingdom

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• R. John Solaro ,

  ¶RJS, XW, YK, and ML are joint senior authors on this work.

  Affiliation Department of Physiology and Biophysics, Center for Cardiovascular Research, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, United States of America

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• Xin Wang ,

  ¶RJS, XW, YK, and ML are joint senior authors on this work.

  Affiliation Faculty of Life Science, University of Manchester, Manchester, United Kingdom

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• Yunbo Ke ,

  * E-mail: yke@uic.edu (YK); ming.lei@pharm.ox.ac.uk (ML)

  ¶RJS, XW, YK, and ML are joint senior authors on this work.

  Affiliation Department of Physiology and Biophysics, Center for Cardiovascular Research, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, United States of America

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• Ming Lei

  * E-mail: yke@uic.edu (YK); ming.lei@pharm.ox.ac.uk (ML)

  ¶RJS, XW, YK, and ML are joint senior authors on this work.

  Affiliations Institute for Cardiovascular Diseases, Union Hospital, Huazhong University of Science and Technology, Wuhan, P. R. China, Department of Pharmacology, University of Oxford, Oxford, United Kingdom

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