Areca Nut Components Affect COX-2, Cyclin B1/cdc25C and Keratin Expression, PGE2 Production in Keratinocyte Is Related to Reactive Oxygen Species, CYP1A1, Src, EGFR and Ras Signaling

• Mei-Chi Chang ,

  Contributed equally to this work with: Mei-Chi Chang, Yi-Jane Chen

  Affiliation Team of Biomedical Science, Chang-Gung University of Science and Technology, Kwei-Shan, Taoyuan, Taiwan

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• Yi-Jane Chen ,

  Contributed equally to this work with: Mei-Chi Chang, Yi-Jane Chen

  Affiliation Laboratory of Pharmacology, Toxicology and Chemical Carcinogenesis, School of Dentistry and Department of Dentistry, National Taiwan University Hospital; and National Taiwan University Medical College, Taipei, Taiwan

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• Hsiao-Hua Chang,

  Affiliation Laboratory of Pharmacology, Toxicology and Chemical Carcinogenesis, School of Dentistry and Department of Dentistry, National Taiwan University Hospital; and National Taiwan University Medical College, Taipei, Taiwan

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• Chiu-Po Chan,

  Affiliation Department of Dentistry, Chang Gung Memorial Hospital, Taipei, Taiwan

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• Chien-Yang Yeh,

  Affiliation Laboratory of Pharmacology, Toxicology and Chemical Carcinogenesis, School of Dentistry and Department of Dentistry, National Taiwan University Hospital; and National Taiwan University Medical College, Taipei, Taiwan

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• Yin-Lin Wang,

  Affiliation Laboratory of Pharmacology, Toxicology and Chemical Carcinogenesis, School of Dentistry and Department of Dentistry, National Taiwan University Hospital; and National Taiwan University Medical College, Taipei, Taiwan

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• Ru-Hsiu Cheng,

  Affiliation Team of Biomedical Science, Chang-Gung University of Science and Technology, Kwei-Shan, Taoyuan, Taiwan

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• Liang-Jiunn Hahn,

  Affiliation Laboratory of Pharmacology, Toxicology and Chemical Carcinogenesis, School of Dentistry and Department of Dentistry, National Taiwan University Hospital; and National Taiwan University Medical College, Taipei, Taiwan

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• Jiiang-Huei Jeng

  * E-mail: jhjeng@ntu.edu.tw

  Affiliation Laboratory of Pharmacology, Toxicology and Chemical Carcinogenesis, School of Dentistry and Department of Dentistry, National Taiwan University Hospital; and National Taiwan University Medical College, Taipei, Taiwan

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