Functional Motor Recovery from Motoneuron Axotomy Is Compromised in Mice with Defective Corticospinal Projections

Yuetong Ding; Yibo Qu; Jia Feng; Meizhi Wang; Qi Han; Kwok-Fai So; Wutian Wu; Libing Zhou

doi:10.1371/journal.pone.0101918

Loading metrics

Open Access

Peer-reviewed

Research Article

Functional Motor Recovery from Motoneuron Axotomy Is Compromised in Mice with Defective Corticospinal Projections

Yuetong Ding,

Affiliations Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, P.R. China, Medical Key Laboratory of Brain Function and Diseases, Jinan University, Guangzhou, P.R. China
⨯
Yibo Qu,

Affiliations Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, P.R. China, Medical Key Laboratory of Brain Function and Diseases, Jinan University, Guangzhou, P.R. China
⨯
Jia Feng,

Affiliations Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, P.R. China, Medical Key Laboratory of Brain Function and Diseases, Jinan University, Guangzhou, P.R. China
⨯
Meizhi Wang,

Affiliations Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, P.R. China, Medical Key Laboratory of Brain Function and Diseases, Jinan University, Guangzhou, P.R. China
⨯
Qi Han,

Affiliations Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, P.R. China, Medical Key Laboratory of Brain Function and Diseases, Jinan University, Guangzhou, P.R. China
⨯
Kwok-Fai So,

Affiliations Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, P.R. China, Medical Key Laboratory of Brain Function and Diseases, Jinan University, Guangzhou, P.R. China, Department of Anatomy LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, P.R. China
⨯
Wutian Wu ,

* E-mail: tlibingzh@jnu.edu.cn (LZ); wtwu@hku.hk (WW)

Affiliations Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, P.R. China, Medical Key Laboratory of Brain Function and Diseases, Jinan University, Guangzhou, P.R. China, Department of Anatomy LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, P.R. China
⨯
Libing Zhou

* E-mail: tlibingzh@jnu.edu.cn (LZ); wtwu@hku.hk (WW)

Affiliations Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, P.R. China, Medical Key Laboratory of Brain Function and Diseases, Jinan University, Guangzhou, P.R. China, Department of Pathophysiology, School of Medicine, Jinan University, Guangzhou, P.R. China, Co-Innovation Center of Neuroregeneration, Nantong University, Jiangsu, P.R. China
⨯

Functional Motor Recovery from Motoneuron Axotomy Is Compromised in Mice with Defective Corticospinal Projections

Yuetong Ding,
Yibo Qu,
Jia Feng,
Meizhi Wang,
Qi Han,
Kwok-Fai So,
Wutian Wu,
Libing Zhou

Published: July 8, 2014
https://doi.org/10.1371/journal.pone.0101918

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Axons
Is the Subject Area "Axons" applicable to this article?

Thanks for your feedback.
Spinal cord
Is the Subject Area "Spinal cord" applicable to this article?

Thanks for your feedback.
Electromyography
Is the Subject Area "Electromyography" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Surgical and invasive medical procedures
Is the Subject Area "Surgical and invasive medical procedures" applicable to this article?

Thanks for your feedback.
Nerve regeneration
Is the Subject Area "Nerve regeneration" applicable to this article?

Thanks for your feedback.
Nerves
Is the Subject Area "Nerves" applicable to this article?

Thanks for your feedback.
Mice
Is the Subject Area "Mice" applicable to this article?

Thanks for your feedback.