Transient and Persistent Metabolomic Changes in Plasma following Chronic Cigarette Smoke Exposure in a Mouse Model

Charmion I. Cruickshank-Quinn; Spencer Mahaffey; Matthew J. Justice; Grant Hughes; Michael Armstrong; Russell P. Bowler; Richard Reisdorph; Irina Petrache; Nichole Reisdorph

doi:10.1371/journal.pone.0101855

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Peer-reviewed

Research Article

Transient and Persistent Metabolomic Changes in Plasma following Chronic Cigarette Smoke Exposure in a Mouse Model

Charmion I. Cruickshank-Quinn,

Affiliation Integrated Department of Immunology, National Jewish Health and University of Colorado School of Medicine, Denver, Colorado, United States of America
⨯
Spencer Mahaffey,

Affiliations Integrated Department of Immunology, National Jewish Health and University of Colorado School of Medicine, Denver, Colorado, United States of America, Department of Pharmacology, School of Medicine, University of Colorado Denver, Aurora, Colorado, United States of America
⨯
Matthew J. Justice,

Affiliation Departments of Medicine and of Biochemistry and Molecular Biology, Indiana University, Indianapolis, Indiana, United States of America
⨯
Grant Hughes,

Affiliation Department of Biostatistics and Informatics, University of Colorado Denver, Aurora, Colorado, United States of America
⨯
Michael Armstrong,

Affiliation Integrated Department of Immunology, National Jewish Health and University of Colorado School of Medicine, Denver, Colorado, United States of America
⨯
Russell P. Bowler,

Affiliation Department of Medicine, National Jewish Health, Denver, Colorado, United States of America
⨯
Richard Reisdorph,

Affiliations Integrated Department of Immunology, National Jewish Health and University of Colorado School of Medicine, Denver, Colorado, United States of America, Department of Pediatrics, National Jewish Health, Denver, Colorado, United States of America
⨯
Irina Petrache ,

* E-mail: ReisdorphN@NJHealth.org (NR); ipetrach@iu.edu (IP)

Affiliations Departments of Medicine and of Biochemistry and Molecular Biology, Indiana University, Indianapolis, Indiana, United States of America, Richard L. Roudebush VA Medical Center, Indianapolis, Indiana, United States of America
⨯
Nichole Reisdorph

* E-mail: ReisdorphN@NJHealth.org (NR); ipetrach@iu.edu (IP)

Affiliation Integrated Department of Immunology, National Jewish Health and University of Colorado School of Medicine, Denver, Colorado, United States of America
⨯

Transient and Persistent Metabolomic Changes in Plasma following Chronic Cigarette Smoke Exposure in a Mouse Model

Charmion I. Cruickshank-Quinn,
Spencer Mahaffey,
Matthew J. Justice,
Grant Hughes,
Michael Armstrong,
Russell P. Bowler,
Richard Reisdorph,
Irina Petrache,
Nichole Reisdorph

Published: July 9, 2014
https://doi.org/10.1371/journal.pone.0101855

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