Downregulation of Blood-Brain Barrier Phenotype by Proinflammatory Cytokines Involves NADPH Oxidase-Dependent ROS Generation: Consequences for Interendothelial Adherens and Tight Junctions

Open Access

Peer-reviewed

Research Article

Keith D. Rochfort,

Affiliation School of Biotechnology, Dublin City University, Dublin, Ireland
⨯
Laura E. Collins,

Affiliation School of Biotechnology, Dublin City University, Dublin, Ireland
⨯
Ronan P. Murphy,

Affiliations School of Health and Human Performance, Dublin City University, Dublin, Ireland, Centre for Preventive Medicine, Dublin City University, Dublin, Ireland
⨯
Philip M. Cummins

Affiliations School of Biotechnology, Dublin City University, Dublin, Ireland, Centre for Preventive Medicine, Dublin City University, Dublin, Ireland
⨯

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Cytokines
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Cytokine therapy
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Protein expression
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Small interfering RNA
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Permeability
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Endothelial cells
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Blood-brain barrier
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Flow cytometry
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