Rapid Phenotypic and Genomic Change in Response to Therapeutic Pressure in Prostate Cancer Inferred by High Content Analysis of Single Circulating Tumor Cells

• Angel E. Dago ,

  Contributed equally to this work with: Angel E. Dago, Asya Stepansky

  Affiliation Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America

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• Asya Stepansky ,

  Contributed equally to this work with: Angel E. Dago, Asya Stepansky

  Affiliations Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America, Skyline Genomics, Roslyn Heights, New York, United States of America

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• Anders Carlsson,

  Affiliation Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America

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• Madelyn Luttgen,

  Affiliation Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America

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• Jude Kendall,

  Affiliations Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America, Skyline Genomics, Roslyn Heights, New York, United States of America

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• Timour Baslan,

  Affiliations Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America, Department of Molecular and Cellular Biology, Stony Brook University, Stony Brook, New York, United States of America

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• Anand Kolatkar,

  Affiliation Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America

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• Michael Wigler,

  Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

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• Kelly Bethel,

  Affiliations Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America, Department of Pathology, Scripps Clinic, La Jolla, California, United States of America

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• Mitchell E. Gross,

  Affiliation Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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• James Hicks ,

  * E-mail: pkuhn@usc.edu (PK); hicks@cshl.edu (JH)

  Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

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• Peter Kuhn

  * E-mail: pkuhn@usc.edu (PK); hicks@cshl.edu (JH)

  Affiliation Dornsife College of Letters, Arts and Sciences, University of Southern California, Los Angeles, California, United States of America

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