Defining the Factors That Contribute to On-Target Specificity of Antisense Oligonucleotides

Open Access

Peer-reviewed

Research Article

Walt F. Lima ,

* E-mail: wlima@isisph.com

Affiliation Isis Pharmaceuticals Inc., Carlsbad, California, United States of America
⨯
Timothy A. Vickers,

Affiliation Isis Pharmaceuticals Inc., Carlsbad, California, United States of America
⨯
Josh Nichols,

Affiliation Isis Pharmaceuticals Inc., Carlsbad, California, United States of America
⨯
Cheryl Li,

Affiliation Isis Pharmaceuticals Inc., Carlsbad, California, United States of America
⨯
Stanley T. Crooke

Affiliation Isis Pharmaceuticals Inc., Carlsbad, California, United States of America
⨯

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Ribonucleases
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Messenger RNA
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RNA denaturation
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RNA hybridization
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RNA structure
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RNA-binding proteins
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Antisense RNA
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Protein extraction
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