The Roles of Individual Mammalian Argonautes in RNA Interference In Vivo

Vera M. Ruda; Rohit Chandwani; Alfica Sehgal; Roman L. Bogorad; Akin Akinc; Klaus Charisse; Alexander Tarakhovsky; Tatiana I. Novobrantseva; Victor Koteliansky

doi:10.1371/journal.pone.0101749

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Open Access

Peer-reviewed

Research Article

The Roles of Individual Mammalian Argonautes in RNA Interference In Vivo

Vera M. Ruda ,

Contributed equally to this work with: Vera M. Ruda, Rohit Chandwani, Alfica Sehgal

* E-mail: rudavera@gmail.com (VMR); v.kotelianski@skolkovotech.ru (VK)

Current address: Novartis Institutes for Biomedical Research, Novartis Pharma AG, Cambridge, Massachusetts, United States of America

Affiliation Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯
Rohit Chandwani ,

Contributed equally to this work with: Vera M. Ruda, Rohit Chandwani, Alfica Sehgal

Affiliation Laboratory of Immune Cell Epigenetics and Signaling, Rockefeller University, New York, New York, United States of America
⨯
Alfica Sehgal ,

Contributed equally to this work with: Vera M. Ruda, Rohit Chandwani, Alfica Sehgal

Affiliation Alnylam Pharmaceuticals, Cambridge, Massachusetts, United States of America
⨯
Roman L. Bogorad,

Affiliation Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯
Akin Akinc,

Affiliation Alnylam Pharmaceuticals, Cambridge, Massachusetts, United States of America
⨯
Klaus Charisse,

Affiliation Alnylam Pharmaceuticals, Cambridge, Massachusetts, United States of America
⨯
Alexander Tarakhovsky,

Affiliation Laboratory of Immune Cell Epigenetics and Signaling, Rockefeller University, New York, New York, United States of America
⨯
Tatiana I. Novobrantseva,

Affiliation Alnylam Pharmaceuticals, Cambridge, Massachusetts, United States of America
⨯
Victor Koteliansky

* E-mail: rudavera@gmail.com (VMR); v.kotelianski@skolkovotech.ru (VK)

Current address: Skolkovo Institute of Science and Technology, Skolkovo, Russian Federation

Affiliation Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯

The Roles of Individual Mammalian Argonautes in RNA Interference In Vivo

Vera M. Ruda,
Rohit Chandwani,
Alfica Sehgal,
Roman L. Bogorad,
Akin Akinc,
Klaus Charisse,
Alexander Tarakhovsky,
Tatiana I. Novobrantseva,
Victor Koteliansky

Published: July 3, 2014
https://doi.org/10.1371/journal.pone.0101749

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Small interfering RNA
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Messenger RNA
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Transfection
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