Exploring the RING-Catalyzed Ubiquitin Transfer Mechanism by MD and QM/MM Calculations

• Yunmei Zhen ,

  Contributed equally to this work with: Yunmei Zhen, Guangrong Qin

  Affiliations Department of Biology, Shantou University, Guangdong, China, Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

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• Guangrong Qin ,

  Contributed equally to this work with: Yunmei Zhen, Guangrong Qin

  Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

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• Cheng Luo,

  Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

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• Hualiang Jiang,

  Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

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• Kunqian Yu ,

  * E-mail: kqyu@mail.shcnc.ac.cn (KY); ghchen@stu.edu.cn (GC)

  Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

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• Guanghui Chen

  * E-mail: kqyu@mail.shcnc.ac.cn (KY); ghchen@stu.edu.cn (GC)

  Affiliation Department of Chemistry, Shantou University, Guangdong, China

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