cAMP Control of HCN2 Channel Mg2+ Block Reveals Loose Coupling between the Cyclic Nucleotide-Gating Ring and the Pore

Open Access

Peer-reviewed

Research Article

cAMP Control of HCN2 Channel Mg²⁺ Block Reveals Loose Coupling between the Cyclic Nucleotide-Gating Ring and the Pore

Alex K. Lyashchenko,

Affiliation Department of Anesthesiology, Columbia University, New York, New York, United States of America
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Kacy J. Redd,

Affiliation Department of Neuroscience, Columbia University, New York, New York, United States of America
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Peter A. Goldstein,

Affiliation Department of Anesthesiology, Weill Cornell Medical College, New York, New York, United States of America
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Gareth R. Tibbs

* E-mail: gareth.r.tibbs@gmail.com

Affiliations Department of Anesthesiology, Columbia University, New York, New York, United States of America, Department of Anesthesiology, Weill Cornell Medical College, New York, New York, United States of America
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Ion channel gating
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Cyclic nucleotide-gated channels
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Nucleotides
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Membrane potential
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Exponential functions
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Extrapolation
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Potassium channels
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Hyperpolarization-activated cyclic nucleotide-gated channels
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