Microstructural Changes in the Striatum and Their Impact on Motor and Neuropsychological Performance in Patients with Multiple Sclerosis

• Michele Cavallari ,

  Contributed equally to this work with: Michele Cavallari, Antonia Ceccarelli

  Affiliations Center for Neurological Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Dipartimento di Neuroscienze, Salute Mentale e Organi di Senso (NESMOS), Università La Sapienza, Rome, Italy

  ⨯
• Antonia Ceccarelli ,

  Contributed equally to this work with: Michele Cavallari, Antonia Ceccarelli

  Affiliation Laboratory for Neuroimaging Research, Department of Neurology, Harvard Medical School, Partners Multiple Sclerosis Center, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

  ⨯
• Guang-Yi Wang,

  Affiliations Center for Neurological Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Radiology, Guangdong General Hospital, Guangzhou, Guangdong Province, People's Republic of China

  ⨯
• Nicola Moscufo,

  Affiliation Center for Neurological Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Salem Hannoun,

  Affiliations Centre de Recherche en Acquisition en Traitement de l'Image pour la Santé (CREATIS), Centre National de la Recherche Scientifique (CNRS) Unités Mixtes de Recherche (UMR) 5220 & Institut National de la Santé et de la Recherche Médicale (INSERM) U1044, Université Claude Bernard - Lyon 1, University of Lyon, Lyon, France, Observatoire Français de la Sclérose en Plaques (OFSEP), University of Lyon, Lyon, France

  ⨯
• Christina R. Matulis,

  Affiliation Laboratory for Neuroimaging Research, Department of Neurology, Harvard Medical School, Partners Multiple Sclerosis Center, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

  ⨯
• Jonathan S. Jackson,

  Affiliation Laboratory for Neuroimaging Research, Department of Neurology, Harvard Medical School, Partners Multiple Sclerosis Center, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

  ⨯
• Bonnie I. Glanz,

  Affiliation Laboratory for Neuroimaging Research, Department of Neurology, Harvard Medical School, Partners Multiple Sclerosis Center, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

  ⨯
• Rohit Bakshi,

  Affiliation Laboratory for Neuroimaging Research, Department of Neurology, Harvard Medical School, Partners Multiple Sclerosis Center, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

  ⨯
• Mohit Neema ,

  ¶‡ These authors also contributed equally to this work and are co-last authors on this work.

  Affiliation Laboratory for Neuroimaging Research, Department of Neurology, Harvard Medical School, Partners Multiple Sclerosis Center, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

  ⨯
• Charles R. G. Guttmann

  * E-mail: guttmann@bwh.harvard.edu

  ¶‡ These authors also contributed equally to this work and are co-last authors on this work.

  Affiliation Center for Neurological Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯