Variability of CSF Alzheimer’s Disease Biomarkers: Implications for Clinical Practice

Stephanie J. B. Vos; Pieter Jelle Visser; Frans Verhey; Pauline Aalten; Dirk Knol; Inez Ramakers; Philip Scheltens; Marcel G. M. Olde. Rikkert; Marcel M. Verbeek; Charlotte E. Teunissen

doi:10.1371/journal.pone.0100784

Loading metrics

Open Access

Peer-reviewed

Research Article

Variability of CSF Alzheimer’s Disease Biomarkers: Implications for Clinical Practice

Stephanie J. B. Vos ,

* E-mail: s.vos@maastrichtuniversity.nl

Affiliation Department of Psychiatry and Neuropsychology, Maastricht University, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht, the Netherlands
⨯
Pieter Jelle Visser,

Affiliations Department of Psychiatry and Neuropsychology, Maastricht University, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht, the Netherlands, Alzheimer center & Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
⨯
Frans Verhey,

Affiliation Department of Psychiatry and Neuropsychology, Maastricht University, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht, the Netherlands
⨯
Pauline Aalten,

Affiliation Department of Psychiatry and Neuropsychology, Maastricht University, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht, the Netherlands
⨯
Dirk Knol,

Affiliation Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands
⨯
Inez Ramakers,

Affiliation Department of Psychiatry and Neuropsychology, Maastricht University, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht, the Netherlands
⨯
Philip Scheltens,

Affiliation Alzheimer center & Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
⨯
Marcel G. M. Olde. Rikkert,

Affiliations Department of Geriatric Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen and Radboud Alzheimer Centre, Nijmegen, The Netherlands
⨯
Marcel M. Verbeek,

Affiliations Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen and Radboud Alzheimer Centre, Nijmegen, The Netherlands, Department of Neurology and Department of Laboratory Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
⨯
Charlotte E. Teunissen

Affiliation Department of Clinical Chemistry, Neurological Laboratory, VU University Medical Center, Amsterdam, The Netherlands
⨯

Variability of CSF Alzheimer’s Disease Biomarkers: Implications for Clinical Practice

Stephanie J. B. Vos,
Pieter Jelle Visser,
Frans Verhey,
Pauline Aalten,
Dirk Knol,
Inez Ramakers,
Philip Scheltens,
Marcel G. M. Olde. Rikkert,
Marcel M. Verbeek,
Charlotte E. Teunissen

Published: June 24, 2014
https://doi.org/10.1371/journal.pone.0100784

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Biomarkers
Is the Subject Area "Biomarkers" applicable to this article?

Thanks for your feedback.
Cerebrospinal fluid
Is the Subject Area "Cerebrospinal fluid" applicable to this article?

Thanks for your feedback.
Alzheimer's disease
Is the Subject Area "Alzheimer's disease" applicable to this article?

Thanks for your feedback.
Learning
Is the Subject Area "Learning" applicable to this article?

Thanks for your feedback.
Cognitive impairment
Is the Subject Area "Cognitive impairment" applicable to this article?

Thanks for your feedback.
Enzyme assays
Is the Subject Area "Enzyme assays" applicable to this article?

Thanks for your feedback.
Government laboratories
Is the Subject Area "Government laboratories" applicable to this article?

Thanks for your feedback.
Dementia
Is the Subject Area "Dementia" applicable to this article?

Thanks for your feedback.