Human Leukocyte Antigen Class II Haplotypes Affect Clinical Characteristics and Progression of Type 1 Autoimmune Hepatitis in Japan

Takeji Umemura; Yoshihiko Katsuyama; Kaname Yoshizawa; Takefumi Kimura; Satoru Joshita; Michiharu Komatsu; Akihiro Matsumoto; Eiji Tanaka; Masao Ota

doi:10.1371/journal.pone.0100565

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Open Access

Peer-reviewed

Research Article

Human Leukocyte Antigen Class II Haplotypes Affect Clinical Characteristics and Progression of Type 1 Autoimmune Hepatitis in Japan

Takeji Umemura ,

* E-mail: tumemura@shinshu-u.ac.jp (TU); otamasao@shinshu-u.ac.jp (MO)

Affiliation Department of Medicine, Division of Hepatology and Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan
⨯
Yoshihiko Katsuyama,

Affiliation Department of Pharmacy, Shinshu University Hospital, Matsumoto, Japan
⨯
Kaname Yoshizawa,

Affiliations Department of Medicine, Division of Hepatology and Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan, Department of Gastroenterology, NHO Ueda Medical Center, Ueda, Japan
⨯
Takefumi Kimura,

Affiliation Department of Medicine, Division of Hepatology and Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan
⨯
Satoru Joshita,

Affiliation Department of Medicine, Division of Hepatology and Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan
⨯
Michiharu Komatsu,

Affiliation Department of Medicine, Division of Hepatology and Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan
⨯
Akihiro Matsumoto,

Affiliation Department of Medicine, Division of Hepatology and Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan
⨯
Eiji Tanaka,

Affiliation Department of Medicine, Division of Hepatology and Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan
⨯
Masao Ota

* E-mail: tumemura@shinshu-u.ac.jp (TU); otamasao@shinshu-u.ac.jp (MO)

Affiliation Department of Legal Medicine, Shinshu University School of Medicine, Matsumoto, Japan
⨯

Human Leukocyte Antigen Class II Haplotypes Affect Clinical Characteristics and Progression of Type 1 Autoimmune Hepatitis in Japan

Takeji Umemura,
Yoshihiko Katsuyama,
Kaname Yoshizawa,
Takefumi Kimura,
Satoru Joshita,
Michiharu Komatsu,
Akihiro Matsumoto,
Eiji Tanaka,
Masao Ota

Published: June 23, 2014
https://doi.org/10.1371/journal.pone.0100565

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Haplotypes
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Disease susceptibility
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Autoimmune hepatitis
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Japan
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Aminotransferases
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