Identifying a Highly-Aggressive DCIS Subgroup by Studying Intra-Individual DCIS Heterogeneity among Invasive Breast Cancer Patients

Dana Pape-Zambito; Zhengyu Jiang; Hong Wu; Karthik Devarajan; Carolyn M. Slater; Kathy Q. Cai; Arthur Patchefsky; Mary B. Daly; Xiaowei Chen

doi:10.1371/journal.pone.0100488

Loading metrics

Open Access

Peer-reviewed

Research Article

Identifying a Highly-Aggressive DCIS Subgroup by Studying Intra-Individual DCIS Heterogeneity among Invasive Breast Cancer Patients

Dana Pape-Zambito ,

Contributed equally to this work with: Dana Pape-Zambito, Zhengyu Jiang

Current address: Department of Biological Sciences, University of the Sciences, Philadelphia, Pennsylvania, United States of America

Affiliation Cancer Epigenetics Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America
⨯
Zhengyu Jiang ,

Contributed equally to this work with: Dana Pape-Zambito, Zhengyu Jiang

Affiliation Cancer Epigenetics Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America
⨯
Hong Wu,

Affiliation Department of Pathology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America
⨯
Karthik Devarajan,

Affiliation Department of Biostatistics and Bioinformatics, Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America
⨯
Carolyn M. Slater,

Affiliation Cancer Epigenetics Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America
⨯
Kathy Q. Cai,

Affiliation Cancer Epigenetics Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America
⨯
Arthur Patchefsky,

Affiliation Department of Pathology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America
⨯
Mary B. Daly,

Affiliation Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America
⨯
Xiaowei Chen

* E-mail: Xiaowei.Chen@fccc.edu

Affiliation Cancer Epigenetics Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America
⨯

Identifying a Highly-Aggressive DCIS Subgroup by Studying Intra-Individual DCIS Heterogeneity among Invasive Breast Cancer Patients

Dana Pape-Zambito,
Zhengyu Jiang,
Hong Wu,
Karthik Devarajan,
Carolyn M. Slater,
Kathy Q. Cai,
Arthur Patchefsky,
Mary B. Daly,
Xiaowei Chen

Published: June 30, 2014
https://doi.org/10.1371/journal.pone.0100488

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Lesions
Is the Subject Area "Lesions" applicable to this article?

Thanks for your feedback.
Breast cancer
Is the Subject Area "Breast cancer" applicable to this article?

Thanks for your feedback.
Immunohistochemistry techniques
Is the Subject Area "Immunohistochemistry techniques" applicable to this article?

Thanks for your feedback.
Biomarkers
Is the Subject Area "Biomarkers" applicable to this article?

Thanks for your feedback.
Cell staining
Is the Subject Area "Cell staining" applicable to this article?

Thanks for your feedback.
Cancer risk factors
Is the Subject Area "Cancer risk factors" applicable to this article?

Thanks for your feedback.
Invasive tumors
Is the Subject Area "Invasive tumors" applicable to this article?

Thanks for your feedback.
Cancer detection and diagnosis
Is the Subject Area "Cancer detection and diagnosis" applicable to this article?

Thanks for your feedback.