Protection from Hemolytic Uremic Syndrome by Eyedrop Vaccination with Modified Enterohemorrhagic E. coli Outer Membrane Vesicles

Kyoung Sub Choi; Sang-Hyun Kim; Eun-Do Kim; Sang-Ho Lee; Soo Jung Han; Sangchul Yoon; Kyu-Tae Chang; Kyoung Yul Seo

doi:10.1371/journal.pone.0100229

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Open Access

Peer-reviewed

Research Article

Protection from Hemolytic Uremic Syndrome by Eyedrop Vaccination with Modified Enterohemorrhagic E. coli Outer Membrane Vesicles

Kyoung Sub Choi ,

Contributed equally to this work with: Kyoung Sub Choi, Sang-Hyun Kim

Affiliations The Graduate School of Yonsei University, Seoul, South Korea, Department of Ophthalmology, National Health Insurance Service Ilsan Hospital, Goyang city, South Korea
⨯
Sang-Hyun Kim ,

Contributed equally to this work with: Kyoung Sub Choi, Sang-Hyun Kim

Affiliation Viral Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, South Korea
⨯
Eun-Do Kim,

Affiliations The Graduate School of Yonsei University, Seoul, South Korea, Department of Ophthalmology, Eye and Ear Hospital, Severance Hospital, Institute of Vision Research, Yonsei University College of Medicine, Seoul, South Korea, Brain Korea 21 Project for Medical Science, Yonsei University, Seoul, South Korea
⨯
Sang-Ho Lee,

Affiliation Viral Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, South Korea
⨯
Soo Jung Han,

Affiliation Department of Ophthalmology, Eye and Ear Hospital, Severance Hospital, Institute of Vision Research, Yonsei University College of Medicine, Seoul, South Korea
⨯
Sangchul Yoon,

Affiliation Department of Ophthalmology, Eye and Ear Hospital, Severance Hospital, Institute of Vision Research, Yonsei University College of Medicine, Seoul, South Korea
⨯
Kyu-Tae Chang ,

* E-mail: seoky@yuhs.ac (KYS); changkt@kribb.re.kr (KTC)

Affiliation The National Primate Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Ochang, Cheongwon, Chungbuk, South Korea
⨯
Kyoung Yul Seo

* E-mail: seoky@yuhs.ac (KYS); changkt@kribb.re.kr (KTC)

Affiliation Department of Ophthalmology, Eye and Ear Hospital, Severance Hospital, Institute of Vision Research, Yonsei University College of Medicine, Seoul, South Korea
⨯

Protection from Hemolytic Uremic Syndrome by Eyedrop Vaccination with Modified Enterohemorrhagic E. coli Outer Membrane Vesicles

Kyoung Sub Choi,
Sang-Hyun Kim,
Eun-Do Kim,
Sang-Ho Lee,
Soo Jung Han,
Sangchul Yoon,
Kyu-Tae Chang,
Kyoung Yul Seo

Published: July 17, 2014
https://doi.org/10.1371/journal.pone.0100229

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