Epimorphin Alters the Inhibitory Effects of SOX9 on Mmp13 in Activated Hepatic Stellate Cells

James Pritchett; Varinder S. Athwal; Emma Harvey; Katherine Martin; Jessica Llewellyn; Philip Ireland; Alexander Nicolaides; Martin J. Humphries; Nicoletta Bobola; Neil A. Hanley; Karen Piper Hanley

doi:10.1371/journal.pone.0100091

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Open Access

Peer-reviewed

Research Article

Epimorphin Alters the Inhibitory Effects of SOX9 on Mmp13 in Activated Hepatic Stellate Cells

James Pritchett ,

Contributed equally to this work with: James Pritchett, Varinder S. Athwal

Affiliations Centre for Endocrinology and Diabetes, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom, Manchester Biomedical Research Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom
⨯
Varinder S. Athwal ,

Contributed equally to this work with: James Pritchett, Varinder S. Athwal

Affiliations Centre for Endocrinology and Diabetes, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom, Manchester Biomedical Research Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom
⨯
Emma Harvey,

Affiliation Centre for Endocrinology and Diabetes, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom
⨯
Katherine Martin,

Affiliations Centre for Endocrinology and Diabetes, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom, Manchester Biomedical Research Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom
⨯
Jessica Llewellyn,

Affiliations Centre for Endocrinology and Diabetes, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom, Manchester Biomedical Research Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom
⨯
Philip Ireland,

Affiliation Centre for Endocrinology and Diabetes, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom
⨯
Alexander Nicolaides,

Affiliation Centre for Endocrinology and Diabetes, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom
⨯
Martin J. Humphries,

Affiliation Wellcome Trust Centre for Cell-Matrix Research, University of Manchester, Manchester, United Kingdom
⨯
Nicoletta Bobola,

Affiliation School of Dentistry, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom
⨯
Neil A. Hanley,

Affiliations Centre for Endocrinology and Diabetes, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom, Manchester Biomedical Research Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom
⨯
Karen Piper Hanley

* E-mail: karen.piperhanley@manchester.ac.uk

Affiliations Centre for Endocrinology and Diabetes, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom, Manchester Biomedical Research Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom
⨯

Epimorphin Alters the Inhibitory Effects of SOX9 on Mmp13 in Activated Hepatic Stellate Cells

James Pritchett,
Varinder S. Athwal,
Emma Harvey,
Katherine Martin,
Jessica Llewellyn,
Philip Ireland,
Alexander Nicolaides,
Martin J. Humphries,
Nicoletta Bobola,
Neil A. Hanley

Published: June 27, 2014
https://doi.org/10.1371/journal.pone.0100091

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