High-Accuracy Identification of Incident HIV-1 Infections Using a Sequence Clustering Based Diversity Measure

Xia-Yu Xia; Meng Ge; Jenny H. Hsi; Xiang He; Yu-Hua Ruan; Zhi-Xin Wang; Yi-Ming Shao; Xian-Ming Pan

doi:10.1371/journal.pone.0100081

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Open Access

Peer-reviewed

Research Article

High-Accuracy Identification of Incident HIV-1 Infections Using a Sequence Clustering Based Diversity Measure

Xia-Yu Xia ,

Contributed equally to this work with: Xia-Yu Xia, Meng Ge, Jenny H. Hsi

Affiliation The Key Laboratory of Bioinformatics, Ministry of Education, School of Life Sciences, Tsinghua University, Beijing, China
⨯
Meng Ge ,

Contributed equally to this work with: Xia-Yu Xia, Meng Ge, Jenny H. Hsi

Current address: The CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China

Affiliation The Key Laboratory of Bioinformatics, Ministry of Education, School of Life Sciences, Tsinghua University, Beijing, China
⨯
Jenny H. Hsi ,

Contributed equally to this work with: Xia-Yu Xia, Meng Ge, Jenny H. Hsi

Affiliation The State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
⨯
Xiang He,

Affiliation The State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
⨯
Yu-Hua Ruan,

Affiliation The State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
⨯
Zhi-Xin Wang,

Affiliation The Key Laboratory of Bioinformatics, Ministry of Education, School of Life Sciences, Tsinghua University, Beijing, China
⨯
Yi-Ming Shao ,

* E-mail: yshao08@gmail.com (YS); pan-xm@mail.tsinghua.edu.cn (XP)

Affiliation The State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
⨯
Xian-Ming Pan

* E-mail: yshao08@gmail.com (YS); pan-xm@mail.tsinghua.edu.cn (XP)

Affiliation The Key Laboratory of Bioinformatics, Ministry of Education, School of Life Sciences, Tsinghua University, Beijing, China
⨯

High-Accuracy Identification of Incident HIV-1 Infections Using a Sequence Clustering Based Diversity Measure

Xia-Yu Xia,
Meng Ge,
Jenny H. Hsi,
Xiang He,
Yu-Hua Ruan,
Zhi-Xin Wang,
Yi-Ming Shao,
Xian-Ming Pan

Published: June 12, 2014
https://doi.org/10.1371/journal.pone.0100081

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HIV-1
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Sequence alignment
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Sequence clustering
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Viral evolution
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Env genes
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