Human 45,X Fibroblast Transcriptome Reveals Distinct Differentially Expressed Genes Including Long Noncoding RNAs Potentially Associated with the Pathophysiology of Turner Syndrome

Shriram N. Rajpathak; Shamsudheen Karuthedath Vellarikkal; Ashok Patowary; Vinod Scaria; Sridhar Sivasubbu; Deepti D. Deobagkar

doi:10.1371/journal.pone.0100076

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Research Article

Human 45,X Fibroblast Transcriptome Reveals Distinct Differentially Expressed Genes Including Long Noncoding RNAs Potentially Associated with the Pathophysiology of Turner Syndrome

Shriram N. Rajpathak ,

Contributed equally to this work with: Shriram N. Rajpathak, Shamsudheen Karuthedath Vellarikkal

¶SR and SKV are joint first authors on this work.

Affiliation Centre of Advanced Studies, Department of Zoology, University of Pune, Pune, India
⨯
Shamsudheen Karuthedath Vellarikkal ,

Contributed equally to this work with: Shriram N. Rajpathak, Shamsudheen Karuthedath Vellarikkal

¶SR and SKV are joint first authors on this work.

Affiliations Genomics and Molecular medicine, CSIR Institute of Genomics and Integrative Biology, Delhi, India, Academy of Scientific and Innovative Research (AcSIR), Anusandhan Bhawan, 2 Rafi Marg, New Delhi, India
⨯
Ashok Patowary,

Affiliation GN Ramachandran Knowledge Centre for Genome Informatics, CSIR Institute of Genomics and Integrative Biology, Delhi, India
⨯
Vinod Scaria ,

* E-mail: vinods@igib.in (VS); s.sivasubbu@igib.res.in (SS); deepti.deobagkar@gmail.com (DD)

Affiliations GN Ramachandran Knowledge Centre for Genome Informatics, CSIR Institute of Genomics and Integrative Biology, Delhi, India, Academy of Scientific and Innovative Research (AcSIR), Anusandhan Bhawan, 2 Rafi Marg, New Delhi, India
⨯
Sridhar Sivasubbu ,

* E-mail: vinods@igib.in (VS); s.sivasubbu@igib.res.in (SS); deepti.deobagkar@gmail.com (DD)

Affiliations Genomics and Molecular medicine, CSIR Institute of Genomics and Integrative Biology, Delhi, India, Academy of Scientific and Innovative Research (AcSIR), Anusandhan Bhawan, 2 Rafi Marg, New Delhi, India
⨯
Deepti D. Deobagkar

* E-mail: vinods@igib.in (VS); s.sivasubbu@igib.res.in (SS); deepti.deobagkar@gmail.com (DD)

Affiliation Centre of Advanced Studies, Department of Zoology, University of Pune, Pune, India
⨯

Human 45,X Fibroblast Transcriptome Reveals Distinct Differentially Expressed Genes Including Long Noncoding RNAs Potentially Associated with the Pathophysiology of Turner Syndrome

Shriram N. Rajpathak,
Shamsudheen Karuthedath Vellarikkal,
Ashok Patowary,
Vinod Scaria,
Sridhar Sivasubbu,
Deepti D. Deobagkar

Published: June 16, 2014
https://doi.org/10.1371/journal.pone.0100076

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Gene expression
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Turner syndrome
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Fibroblasts
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Gene regulation
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Long non-coding RNA
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RNA sequencing
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Transcriptome analysis
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Bone development
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