Systemic Sclerosis Immunoglobulin Induces Growth and a Pro-Fibrotic State in Vascular Smooth Muscle Cells through the Epidermal Growth Factor Receptor

Open Access

Peer-reviewed

Research Article

Monique R. Arts,

Affiliations Université de Montréal, Faculté de Pharmacie, Montreal, Quebec, Canada, McGill University, Jewish General Hospital, Montreal, Quebec, Canada
⨯
Murray Baron,

Affiliation McGill University, Jewish General Hospital, Montreal, Quebec, Canada
⨯
Nidaa Chokr,

Affiliation Université de Montréal, Faculté de Pharmacie, Montreal, Quebec, Canada
⨯
Marvin J. Fritzler,

Affiliation Department of Medicine, University of Calgary, Calgary, Alberta, Canada
⨯
the Canadian Scleroderma Research Group (CSRG) ,

¶Membership of the Canadian Scleroderma Research Group (CSRG) is provided in the Acknowledgments
⨯
Marc J. Servant

* E-mail: marc.servant@umontreal.ca

Affiliation Université de Montréal, Faculté de Pharmacie, Montreal, Quebec, Canada
⨯

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Autoantibodies
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Immunoprecipitation
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Protein synthesis
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EGFR signaling
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Enzyme-linked immunoassays
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Epidermal growth factor
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Gene expression
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Smooth muscle cells
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