An Examination of the Relationship between Hotspots and Recombination Associated with Chromosome 21 Nondisjunction

Tiffany Renee Oliver; Candace D. Middlebrooks; Stuart W. Tinker; Emily Graves Allen; Lora J. H. Bean; Ferdouse Begum; Eleanor Feingold; Reshmi Chowdhury; Vivian Cheung; Stephanie L. Sherman

doi:10.1371/journal.pone.0099560

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Open Access

Peer-reviewed

Research Article

An Examination of the Relationship between Hotspots and Recombination Associated with Chromosome 21 Nondisjunction

Tiffany Renee Oliver ,

Contributed equally to this work with: Tiffany Renee Oliver, Candace D. Middlebrooks

* E-mail: Toliver4@spelman.edu

Affiliations Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America, Department of Biology, Spelman College, Atlanta, Georgia, United States of America
⨯
Candace D. Middlebrooks ,

Contributed equally to this work with: Tiffany Renee Oliver, Candace D. Middlebrooks

Affiliation Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Stuart W. Tinker,

Affiliation Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Emily Graves Allen,

Affiliation Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Lora J. H. Bean,

Affiliation Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Ferdouse Begum,

Affiliation Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Eleanor Feingold,

Affiliations Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Human Genetics, Graduate School of Public Health University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Reshmi Chowdhury,

Affiliation Department of Human Genetics, Graduate School of Public Health University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Vivian Cheung,

Affiliations Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America
⨯
Stephanie L. Sherman

Affiliation Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯

An Examination of the Relationship between Hotspots and Recombination Associated with Chromosome 21 Nondisjunction

Tiffany Renee Oliver,
Candace D. Middlebrooks,
Stuart W. Tinker,
Emily Graves Allen,
Lora J. H. Bean,
Ferdouse Begum,
Eleanor Feingold,
Reshmi Chowdhury,
Vivian Cheung,
Stephanie L. Sherman

Published: June 13, 2014
https://doi.org/10.1371/journal.pone.0099560

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