Astrocytic Toll-Like Receptor 3 Is Associated with Ischemic Preconditioning- Induced Protection against Brain Ischemia in Rodents

Lin-na Pan; Wei Zhu; Yang Li; Xu-lin Xu; Lian-jun Guo; Qing Lu; Jian Wang

doi:10.1371/journal.pone.0099526

Loading metrics

Open Access

Peer-reviewed

Research Article

Astrocytic Toll-Like Receptor 3 Is Associated with Ischemic Preconditioning- Induced Protection against Brain Ischemia in Rodents

Lin-na Pan ,

Contributed equally to this work with: Lin-na Pan, Wei Zhu

Affiliations Department of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China, Medical Department of Neurology, The Second Hospital of Nanchang, Nanchang, Jiangxi, People's Republic of China
⨯
Wei Zhu ,

Contributed equally to this work with: Lin-na Pan, Wei Zhu

Affiliations Department of Emergency Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, School of Medicine, Baltimore, Maryland, United States of America
⨯
Yang Li,

Affiliation Department of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China
⨯
Xu-lin Xu,

Affiliations Department of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China, The Key Laboratory of Drug Target Research and Pharmacodynamic Evaluation, Hubei Province, Wuhan, Hubei, People's Republic of China
⨯
Lian-jun Guo,

Affiliations Department of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China, The Key Laboratory of Drug Target Research and Pharmacodynamic Evaluation, Hubei Province, Wuhan, Hubei, People's Republic of China
⨯
Qing Lu ,

* E-mail: qinglu@mail.hust.edu.cn

Affiliations Department of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China, The Key Laboratory of Drug Target Research and Pharmacodynamic Evaluation, Hubei Province, Wuhan, Hubei, People's Republic of China
⨯
Jian Wang

Affiliation Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, School of Medicine, Baltimore, Maryland, United States of America
⨯

Astrocytic Toll-Like Receptor 3 Is Associated with Ischemic Preconditioning- Induced Protection against Brain Ischemia in Rodents

Lin-na Pan,
Wei Zhu,
Yang Li,
Xu-lin Xu,
Lian-jun Guo,
Qing Lu,
Jian Wang

Published: June 10, 2014
https://doi.org/10.1371/journal.pone.0099526

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Astrocytes
Is the Subject Area "Astrocytes" applicable to this article?

Thanks for your feedback.
Toll-like receptors
Is the Subject Area "Toll-like receptors" applicable to this article?

Thanks for your feedback.
Immune receptor signaling
Is the Subject Area "Immune receptor signaling" applicable to this article?

Thanks for your feedback.
Cerebral ischemia
Is the Subject Area "Cerebral ischemia" applicable to this article?

Thanks for your feedback.
Brain damage
Is the Subject Area "Brain damage" applicable to this article?

Thanks for your feedback.
Ischemia
Is the Subject Area "Ischemia" applicable to this article?

Thanks for your feedback.
Transcription factors
Is the Subject Area "Transcription factors" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.