Mutation of Serine 1333 in the ATR HEAT Repeats Creates a Hyperactive Kinase

Open Access

Peer-reviewed

Research Article

Jessica W. Luzwick,

Affiliation Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Edward A. Nam,

Affiliation Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Runxiang Zhao,

Affiliation Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
David Cortez

* E-mail: david.cortez@vanderbilt.edu

Affiliation Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯

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Phosphorylation
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DNA replication
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In vitro kinase assay
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DNA-binding proteins
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DNA damage
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Immunoblotting
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Protein structure prediction
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Synthesis phase
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