N-Octanoyl Dopamine Treatment of Endothelial Cells Induces the Unfolded Protein Response and Results in Hypometabolism and Tolerance to Hypothermia

Eleni Stamellou; Johann Fontana; Johannes Wedel; Emmanouil Ntasis; Carsten Sticht; Anja Becker; Prama Pallavi; Kerstin Wolf; Bernhard K. Krämer; Mathias Hafner; Willem J. van Son; Benito A. Yard

doi:10.1371/journal.pone.0099298

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Open Access

Peer-reviewed

Research Article

N-Octanoyl Dopamine Treatment of Endothelial Cells Induces the Unfolded Protein Response and Results in Hypometabolism and Tolerance to Hypothermia

Eleni Stamellou ,

* E-mail: stamellou.eleni@googlemail.com

Affiliation Vth. Medical Department, Medical Faculty Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany
⨯
Johann Fontana,

Affiliation Department of Neurosurgery, Ruhr-University Bochum, Bochum, Germany
⨯
Johannes Wedel,

Affiliation Vth. Medical Department, Medical Faculty Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany
⨯
Emmanouil Ntasis,

Affiliation Vth. Medical Department, Medical Faculty Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany
⨯
Carsten Sticht,

Affiliation Medical Research Centre (ZMF), Medical Faculty Mannheim University of Heidelberg, Mannheim, Germany
⨯
Anja Becker,

Affiliation Institute for Molecular and Cellular Biology, Mannheim University of Applied Sciences, Mannheim, Germany
⨯
Prama Pallavi,

Affiliation Vth. Medical Department, Medical Faculty Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany
⨯
Kerstin Wolf,

Affiliation Institute for Molecular and Cellular Biology, Mannheim University of Applied Sciences, Mannheim, Germany
⨯
Bernhard K. Krämer,

Affiliation Vth. Medical Department, Medical Faculty Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany
⨯
Mathias Hafner,

Affiliation Institute for Molecular and Cellular Biology, Mannheim University of Applied Sciences, Mannheim, Germany
⨯
Willem J. van Son,

Affiliation Department of Nephrology, Academic Medical Centre, Groningen, the Netherlands
⨯
Benito A. Yard

Affiliation Vth. Medical Department, Medical Faculty Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany
⨯

N-Octanoyl Dopamine Treatment of Endothelial Cells Induces the Unfolded Protein Response and Results in Hypometabolism and Tolerance to Hypothermia

Eleni Stamellou,
Johann Fontana,
Johannes Wedel,
Emmanouil Ntasis,
Carsten Sticht,
Anja Becker,
Prama Pallavi,
Kerstin Wolf,
Bernhard K. Krämer,
Mathias Hafner

Published: June 13, 2014
https://doi.org/10.1371/journal.pone.0099298

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Gene expression
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Endoplasmic reticulum
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