Cabergoline, Dopamine D2 Receptor Agonist, Prevents Neuronal Cell Death under Oxidative Stress via Reducing Excitotoxicity

Haruki Odaka; Tadahiro Numakawa; Naoki Adachi; Yoshiko Ooshima; Shingo Nakajima; Yusuke Katanuma; Takafumi Inoue; Hiroshi Kunugi

doi:10.1371/journal.pone.0099271

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Open Access

Peer-reviewed

Research Article

Cabergoline, Dopamine D2 Receptor Agonist, Prevents Neuronal Cell Death under Oxidative Stress via Reducing Excitotoxicity

Haruki Odaka,

Affiliations Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan, Department of Life Science and Medical Bioscience, School of Advanced Science and Engineering, Waseda University, Tokyo, Japan
⨯
Tadahiro Numakawa ,

* E-mail: numakawa@ncnp.go.jp

Affiliations Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan, Core Research for Evolution Science and Technology Program (CREST), Japan Science and Technology Agency (JST), Tokyo, Japan
⨯
Naoki Adachi,

Affiliations Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan, Core Research for Evolution Science and Technology Program (CREST), Japan Science and Technology Agency (JST), Tokyo, Japan
⨯
Yoshiko Ooshima,

Affiliation Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan
⨯
Shingo Nakajima,

Affiliations Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan, Core Research for Evolution Science and Technology Program (CREST), Japan Science and Technology Agency (JST), Tokyo, Japan
⨯
Yusuke Katanuma,

Affiliations Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan, Department of Life Science and Medical Bioscience, School of Advanced Science and Engineering, Waseda University, Tokyo, Japan
⨯
Takafumi Inoue,

Affiliation Department of Life Science and Medical Bioscience, School of Advanced Science and Engineering, Waseda University, Tokyo, Japan
⨯
Hiroshi Kunugi

Affiliations Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan, Core Research for Evolution Science and Technology Program (CREST), Japan Science and Technology Agency (JST), Tokyo, Japan
⨯

Cabergoline, Dopamine D2 Receptor Agonist, Prevents Neuronal Cell Death under Oxidative Stress via Reducing Excitotoxicity

Haruki Odaka,
Tadahiro Numakawa,
Naoki Adachi,
Yoshiko Ooshima,
Shingo Nakajima,
Yusuke Katanuma,
Takafumi Inoue,
Hiroshi Kunugi

Published: June 10, 2014
https://doi.org/10.1371/journal.pone.0099271

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