Leptin Is an Anti-Apoptotic Effector in Placental Cells Involving p53 Downregulation

Ayelén Rayen Toro; Julieta Lorena Maymó; Federico Matías Ibarbalz; Antonio Pérez Pérez; Bernardo Maskin; Alicia Graciela Faletti; Víctor Sánchez Margalet; Cecilia Laura Varone

doi:10.1371/journal.pone.0099187

Loading metrics

Open Access

Peer-reviewed

Research Article

Leptin Is an Anti-Apoptotic Effector in Placental Cells Involving p53 Downregulation

Ayelén Rayen Toro,

Affiliation Departamento de Química Biológica, Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
⨯
Julieta Lorena Maymó,

Affiliation Departamento de Química Biológica, Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
⨯
Federico Matías Ibarbalz,

Affiliation Departamento de Química Biológica, Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
⨯
Antonio Pérez Pérez,

Affiliation Departamento de Bioquímica Médica y Biología Molecular, Hospital Universitario Virgen Macarena, Facultad de Medicina, Universidad de Sevilla, Sevilla, España
⨯
Bernardo Maskin,

Affiliation Hospital Nacional Profesor Alejandro Posadas, Buenos Aires, Argentina
⨯
Alicia Graciela Faletti,

Affiliation Centro de Estudios Farmacológicos y Botánicos, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina
⨯
Víctor Sánchez Margalet,

Affiliation Departamento de Bioquímica Médica y Biología Molecular, Hospital Universitario Virgen Macarena, Facultad de Medicina, Universidad de Sevilla, Sevilla, España
⨯
Cecilia Laura Varone

* E-mail: cvarone@qb.fcen.uba.ar

Affiliation Departamento de Química Biológica, Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
⨯

Leptin Is an Anti-Apoptotic Effector in Placental Cells Involving p53 Downregulation

Ayelén Rayen Toro,
Julieta Lorena Maymó,
Federico Matías Ibarbalz,
Antonio Pérez Pérez,
Bernardo Maskin,
Alicia Graciela Faletti,
Víctor Sánchez Margalet,
Cecilia Laura Varone

Published: June 12, 2014
https://doi.org/10.1371/journal.pone.0099187

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Leptin
Is the Subject Area "Leptin" applicable to this article?

Thanks for your feedback.
Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.
Trophoblasts
Is the Subject Area "Trophoblasts" applicable to this article?

Thanks for your feedback.
Phosphorylation
Is the Subject Area "Phosphorylation" applicable to this article?

Thanks for your feedback.
Protein extraction
Is the Subject Area "Protein extraction" applicable to this article?

Thanks for your feedback.
Placenta
Is the Subject Area "Placenta" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Pregnancy
Is the Subject Area "Pregnancy" applicable to this article?

Thanks for your feedback.