Development and Evaluation of Small Peptidomimetic Ligands to Protease-Activated Receptor-2 (PAR2) through the Use of Lipid Tethering

Scott Boitano; Justin Hoffman; Dipti V. Tillu; Marina N. Asiedu; Zhenyu Zhang; Cara L. Sherwood; Yan Wang; Xinzhong Dong; Theodore J. Price; Josef Vagner

doi:10.1371/journal.pone.0099140

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Peer-reviewed

Research Article

Development and Evaluation of Small Peptidomimetic Ligands to Protease-Activated Receptor-2 (PAR₂) through the Use of Lipid Tethering

Scott Boitano ,

* E-mail: sboitano@email.arizona.edu (SB); vagner@email.arizona.edu (JV); tjp140130@utdallas.edu (TJP)

Affiliations Arizona Respiratory Center and Department of Physiology, University of Arizona, Tucson, Arizona, United States of America, The BIO5 Collaborative Research Institute, University of Arizona, Tucson, Arizona, United States of America
⨯
Justin Hoffman,

Affiliations Arizona Respiratory Center and Department of Physiology, University of Arizona, Tucson, Arizona, United States of America, The BIO5 Collaborative Research Institute, University of Arizona, Tucson, Arizona, United States of America
⨯
Dipti V. Tillu,

Affiliation Department of Pharmacology, University of Arizona, Tucson, Arizona, United States of America
⨯
Marina N. Asiedu,

Affiliation Department of Pharmacology, University of Arizona, Tucson, Arizona, United States of America
⨯
Zhenyu Zhang,

Affiliation The BIO5 Collaborative Research Institute, University of Arizona, Tucson, Arizona, United States of America
⨯
Cara L. Sherwood,

Affiliations Arizona Respiratory Center and Department of Physiology, University of Arizona, Tucson, Arizona, United States of America, The BIO5 Collaborative Research Institute, University of Arizona, Tucson, Arizona, United States of America
⨯
Yan Wang,

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
Xinzhong Dong,

Affiliation Department of Neuroscience, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Theodore J. Price ,

* E-mail: sboitano@email.arizona.edu (SB); vagner@email.arizona.edu (JV); tjp140130@utdallas.edu (TJP)

Affiliations The BIO5 Collaborative Research Institute, University of Arizona, Tucson, Arizona, United States of America, Department of Pharmacology, University of Arizona, Tucson, Arizona, United States of America
⨯
Josef Vagner

* E-mail: sboitano@email.arizona.edu (SB); vagner@email.arizona.edu (JV); tjp140130@utdallas.edu (TJP)

Affiliation The BIO5 Collaborative Research Institute, University of Arizona, Tucson, Arizona, United States of America
⨯

Development and Evaluation of Small Peptidomimetic Ligands to Protease-Activated Receptor-2 (PAR₂) through the Use of Lipid Tethering

Scott Boitano,
Justin Hoffman,
Dipti V. Tillu,
Marina N. Asiedu,
Zhenyu Zhang,
Cara L. Sherwood,
Yan Wang,
Xinzhong Dong,
Theodore J. Price,
Josef Vagner

Published: June 13, 2014
https://doi.org/10.1371/journal.pone.0099140

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