MicroRNA Profiling in Muc2 Knockout Mice of Colitis-Associated Cancer Model Reveals Epigenetic Alterations during Chronic Colitis Malignant Transformation

Yonghua Bao; Yongchen Guo; Zexin Li; Wenfeng Fang; Yiqiong Yang; Xuhan Li; Zhuangzhuang Li; Bowen Xiong; Zhiguo Chen; Jianguo Wang; Kang Kang; Deming Gou; Wancai Yang

doi:10.1371/journal.pone.0099132

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Open Access

Peer-reviewed

Research Article

MicroRNA Profiling in Muc2 Knockout Mice of Colitis-Associated Cancer Model Reveals Epigenetic Alterations during Chronic Colitis Malignant Transformation

Yonghua Bao ,

Contributed equally to this work with: Yonghua Bao, Yongchen Guo

Affiliation Department of Immunology, Xinxiang Medical University, Xinxiang, China
⨯
Yongchen Guo ,

Contributed equally to this work with: Yonghua Bao, Yongchen Guo

Affiliation Department of Laboratory Medicine, Xinxiang Medical University, Xinxiang, China
⨯
Zexin Li,

Affiliation Department of Surgery, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China
⨯
Wenfeng Fang,

Affiliation Department of Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China
⨯
Yiqiong Yang,

Affiliation School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, China
⨯
Xuhan Li,

Affiliation School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, China
⨯
Zhuangzhuang Li,

Affiliation School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, China
⨯
Bowen Xiong,

Affiliation School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, China
⨯
Zhiguo Chen,

Affiliation School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, China
⨯
Jianguo Wang,

Affiliation Department of Surgery, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China
⨯
Kang Kang,

Affiliation School of Life Sciences, Shenzhen University, Shenzhen, China
⨯
Deming Gou,

Affiliation School of Life Sciences, Shenzhen University, Shenzhen, China
⨯
Wancai Yang

* E-mail: wyang06@uic.edu

Affiliations School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, China, Department of Pathology, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯

MicroRNA Profiling in Muc2 Knockout Mice of Colitis-Associated Cancer Model Reveals Epigenetic Alterations during Chronic Colitis Malignant Transformation

Yonghua Bao,
Yongchen Guo,
Zexin Li,
Wenfeng Fang,
Yiqiong Yang,
Xuhan Li,
Zhuangzhuang Li,
Bowen Xiong,
Zhiguo Chen,
Jianguo Wang

Published: June 18, 2014
https://doi.org/10.1371/journal.pone.0099132

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