Interleukin-17A Promotes MUC5AC Expression and Goblet Cell Hyperplasia in Nasal Polyps via the Act1-Mediated Pathway

Wentong Xia; Jing Bai; Xingmei Wu; Yi Wei; Shaoyan Feng; Lei Li; Jia Zhang; Guanxia Xiong; Yunping Fan; Jianbo Shi; Huabin Li

doi:10.1371/journal.pone.0098915

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Open Access

Peer-reviewed

Research Article

Interleukin-17A Promotes MUC5AC Expression and Goblet Cell Hyperplasia in Nasal Polyps via the Act1-Mediated Pathway

Wentong Xia ,

Contributed equally to this work with: Wentong Xia, Jing Bai, Xingmei Wu

Affiliations Allergy and Cancer Center, Otorhinolarygology Hospital, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, Department of Otolaryngology, Head and Neck Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
⨯
Jing Bai ,

Contributed equally to this work with: Wentong Xia, Jing Bai, Xingmei Wu

Affiliation Allergy and Cancer Center, Otorhinolarygology Hospital, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
⨯
Xingmei Wu ,

Contributed equally to this work with: Wentong Xia, Jing Bai, Xingmei Wu

Affiliation Allergy and Cancer Center, Otorhinolarygology Hospital, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
⨯
Yi Wei,

Affiliation Allergy and Cancer Center, Otorhinolarygology Hospital, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
⨯
Shaoyan Feng,

Affiliation Department of Otolaryngology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China
⨯
Lei Li,

Affiliation Department of Otolaryngology, Head and Neck Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
⨯
Jia Zhang,

Affiliation Allergy and Cancer Center, Otorhinolarygology Hospital, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
⨯
Guanxia Xiong,

Affiliation Allergy and Cancer Center, Otorhinolarygology Hospital, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
⨯
Yunping Fan,

Affiliation Department of Otolaryngology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China
⨯
Jianbo Shi,

Affiliation Allergy and Cancer Center, Otorhinolarygology Hospital, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
⨯
Huabin Li

* E-mail: allergyli@163.com

Affiliations Allergy and Cancer Center, Otorhinolarygology Hospital, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, Department of Otolaryngology, Head and Neck Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
⨯

Interleukin-17A Promotes MUC5AC Expression and Goblet Cell Hyperplasia in Nasal Polyps via the Act1-Mediated Pathway

Wentong Xia,
Jing Bai,
Xingmei Wu,
Yi Wei,
Shaoyan Feng,
Lei Li,
Jia Zhang,
Guanxia Xiong,
Yunping Fan,
Jianbo Shi

Published: June 3, 2014
https://doi.org/10.1371/journal.pone.0098915

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