Genetic Association of Objective Sleep Phenotypes with a Functional Polymorphism in the Neuropeptide S Receptor Gene

Janek Spada; Christian Sander; Ralph Burkhardt; Madlen Häntzsch; Roland Mergl; Markus Scholz; Ulrich Hegerl; Tilman Hensch

doi:10.1371/journal.pone.0098789

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Peer-reviewed

Research Article

Genetic Association of Objective Sleep Phenotypes with a Functional Polymorphism in the Neuropeptide S Receptor Gene

Janek Spada ,

* E-mail: janek.spada@medizin.uni-leipzig.de

Affiliations LIFE – Leipzig Research Center for Civilization Diseases, Universität Leipzig, Leipzig, Germany, Department of Psychiatry and Psychotherapy, Universität Leipzig, Leipzig, Germany
⨯
Christian Sander,

Affiliations LIFE – Leipzig Research Center for Civilization Diseases, Universität Leipzig, Leipzig, Germany, Department of Psychiatry and Psychotherapy, Universität Leipzig, Leipzig, Germany
⨯
Ralph Burkhardt,

Affiliations LIFE – Leipzig Research Center for Civilization Diseases, Universität Leipzig, Leipzig, Germany, Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany
⨯
Madlen Häntzsch,

Affiliations LIFE – Leipzig Research Center for Civilization Diseases, Universität Leipzig, Leipzig, Germany, Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany
⨯
Roland Mergl,

Affiliations LIFE – Leipzig Research Center for Civilization Diseases, Universität Leipzig, Leipzig, Germany, Department of Psychiatry and Psychotherapy, Universität Leipzig, Leipzig, Germany
⨯
Markus Scholz,

Affiliations LIFE – Leipzig Research Center for Civilization Diseases, Universität Leipzig, Leipzig, Germany, Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Universität Leipzig, Leipzig, Germany
⨯
Ulrich Hegerl,

Affiliations LIFE – Leipzig Research Center for Civilization Diseases, Universität Leipzig, Leipzig, Germany, Department of Psychiatry and Psychotherapy, Universität Leipzig, Leipzig, Germany
⨯
Tilman Hensch

Affiliations LIFE – Leipzig Research Center for Civilization Diseases, Universität Leipzig, Leipzig, Germany, Department of Psychiatry and Psychotherapy, Universität Leipzig, Leipzig, Germany
⨯

Genetic Association of Objective Sleep Phenotypes with a Functional Polymorphism in the Neuropeptide S Receptor Gene

Janek Spada,
Christian Sander,
Ralph Burkhardt,
Madlen Häntzsch,
Roland Mergl,
Markus Scholz,
Ulrich Hegerl,
Tilman Hensch

Published: June 4, 2014
https://doi.org/10.1371/journal.pone.0098789

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Sleep
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Single nucleotide polymorphisms
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Neurons
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Neuropeptides
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Genotyping
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Genome-wide association studies
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Homozygosity
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