Shaking Alone Induces De Novo Conversion of Recombinant Prion Proteins to β-Sheet Rich Oligomers and Fibrils

Open Access

Peer-reviewed

Research Article

Carol L. Ladner-Keay,

Affiliations Department of Computing Science, University of Alberta, Edmonton, Alberta, Canada, Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada, National Institute for Nanotechnology, Edmonton, Alberta, Canada
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Bethany J. Griffith,

Affiliations Department of Computing Science, University of Alberta, Edmonton, Alberta, Canada, National Institute for Nanotechnology, Edmonton, Alberta, Canada
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David S. Wishart

* E-mail: david.wishart@ualberta.ca

Affiliations Department of Computing Science, University of Alberta, Edmonton, Alberta, Canada, Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada, National Institute for Nanotechnology, Edmonton, Alberta, Canada
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Oligomers
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Sonication
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Amyloid proteins
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Prion diseases
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Electron microscopy
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Urea
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Animal prion diseases
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Monomers
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