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Open Access

Peer-reviewed

Research Article

A Novel Herbal Medicine, KIOM-C, Induces Autophagic and Apoptotic Cell Death Mediated by Activation of JNK and Reactive Oxygen Species in HT1080 Human Fibrosarcoma Cells

Aeyung Kim,

Affiliation Korean Medicine (KM)-Based Herbal Drug Development Group, Korea Institute of Oriental Medicine (KIOM), Daejeon, Republic of Korea
⨯
Minju Im,

Affiliation Korean Medicine (KM)-Based Herbal Drug Development Group, Korea Institute of Oriental Medicine (KIOM), Daejeon, Republic of Korea
⨯
Nam-Hui Yim,

Affiliation Korean Medicine (KM)-Based Herbal Drug Development Group, Korea Institute of Oriental Medicine (KIOM), Daejeon, Republic of Korea
⨯
Taesoo Kim,

Affiliation Korean Medicine (KM)-Based Herbal Drug Development Group, Korea Institute of Oriental Medicine (KIOM), Daejeon, Republic of Korea
⨯
Jin Yeul Ma

* E-mail: jyma@kiom.re.kr

Affiliation Korean Medicine (KM)-Based Herbal Drug Development Group, Korea Institute of Oriental Medicine (KIOM), Daejeon, Republic of Korea
⨯

A Novel Herbal Medicine, KIOM-C, Induces Autophagic and Apoptotic Cell Death Mediated by Activation of JNK and Reactive Oxygen Species in HT1080 Human Fibrosarcoma Cells

Aeyung Kim,
Minju Im,
Nam-Hui Yim,
Taesoo Kim,
Jin Yeul Ma

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Published: May 30, 2014
https://doi.org/10.1371/journal.pone.0098703

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Apoptosis
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Autophagic cell death
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HT1080 cells
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Cancer treatment
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Renal cancer
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Lung and intrathoracic tumors
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Small interfering RNA
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