Endothelial Depletion of Acvrl1 in Mice Leads to Arteriovenous Malformations Associated with Reduced Endoglin Expression

• Simon Tual-Chalot ,

  Contributed equally to this work with: Simon Tual-Chalot, Marwa Mahmoud

  Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle, United Kingdom

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• Marwa Mahmoud ,

  Contributed equally to this work with: Simon Tual-Chalot, Marwa Mahmoud

  Current address: Centre for Cardiovascular Biology & Medicine, UCL Medical School, London, United Kingdom,

  Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle, United Kingdom

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• Kathleen R. Allinson,

  Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle, United Kingdom

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• Rachael E. Redgrave,

  Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle, United Kingdom

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• Zhenhua Zhai,

  Current address: Cancer and Vascular Biology Laboratory, Liaoning Medical University, Jinzhou City, Liaoning Province, China

  Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle, United Kingdom

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• S. Paul Oh,

  Affiliation Department of Physiology, University of Florida, Gainesville, Florida, United States of America

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• Marcus Fruttiger,

  Affiliation UCL, Institute of Opthalmology, London, United Kingdom

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• Helen M. Arthur

  * E-mail: helen.arthur@ncl.ac.uk

  Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle, United Kingdom

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