Sinomenine Sensitizes Multidrug-Resistant Colon Cancer Cells (Caco-2) to Doxorubicin by Downregulation of MDR-1 Expression

Open Access

Peer-reviewed

Research Article

Zhen Liu,

Affiliation Department of Gastroenterology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China
⨯
Zhi-Jun Duan ,

* E-mail: cathydoctor@sina.com (ZJD); qychang0409@163.com (QYC)

Affiliation Department of Gastroenterology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China
⨯
Jiu-Yang Chang,

Affiliation Department of Gastroenterology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China
⨯
Zhi-feng Zhang,

Affiliation Department of Gastroenterology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China
⨯
Rui Chu,

Affiliation Department of Gastroenterology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China
⨯
Yu-Ling Li,

Affiliation Department of Gastroenterology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China
⨯
Ke-Hang Dai,

Affiliation Department of Gastroenterology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China
⨯
Guang-quan Mo,

Affiliation Department of Gastroenterology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China
⨯
Qing-Yong Chang

* E-mail: cathydoctor@sina.com (ZJD); qychang0409@163.com (QYC)

Affiliation Department of Neurosurgery, Zhongshan Affiliated Hospital of Dalian University, Dalian, Liaoning, China
⨯

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Caco-2 cells
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Transcription factors
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COX-2 inhibitors
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Colorectal cancer
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Cancer treatment
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Polymerase chain reaction
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Lung and intrathoracic tumors
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Breast cancer
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