A Loss of Function Analysis of Host Factors Influencing Vaccinia virus Replication by RNA Interference

Philippa M. Beard; Samantha J. Griffiths; Orland Gonzalez; Ismar R. Haga; Tali Pechenick Jowers; Danielle K. Reynolds; Jan Wildenhain; Hille Tekotte; Manfred Auer; Mike Tyers; Peter Ghazal; Ralf Zimmer; Jürgen Haas

doi:10.1371/journal.pone.0098431

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Open Access

Peer-reviewed

Research Article

A Loss of Function Analysis of Host Factors Influencing Vaccinia virus Replication by RNA Interference

Philippa M. Beard ,

Contributed equally to this work with: Philippa M. Beard, Samantha J. Griffiths

* E-mail: pip.beard@roslin.ed.ac.uk (PMB); juergen.haas@ed.ac.uk (JH)

Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, Midlothian, United Kingdom
⨯
Samantha J. Griffiths ,

Contributed equally to this work with: Philippa M. Beard, Samantha J. Griffiths

Affiliation Division of Pathway Medicine, University of Edinburgh, Edinburgh, Midlothian, United Kingdom
⨯
Orland Gonzalez,

Affiliation Institute for Informatics, Ludwig-Maximilians-Universität München, München, Germany
⨯
Ismar R. Haga,

Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, Midlothian, United Kingdom
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Tali Pechenick Jowers,

Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, Midlothian, United Kingdom
⨯
Danielle K. Reynolds,

Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, Midlothian, United Kingdom
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Jan Wildenhain,

Affiliation Wellcome Trust Centre for Cell Biology, University of Edinburgh, Kings Buildings, Edinburgh, Midlothian, United Kingdom
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Hille Tekotte,

Affiliation Wellcome Trust Centre for Cell Biology, University of Edinburgh, Kings Buildings, Edinburgh, Midlothian, United Kingdom
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Manfred Auer,

Affiliation Wellcome Trust Centre for Cell Biology, University of Edinburgh, Kings Buildings, Edinburgh, Midlothian, United Kingdom
⨯
Mike Tyers,

Affiliations Wellcome Trust Centre for Cell Biology, University of Edinburgh, Kings Buildings, Edinburgh, Midlothian, United Kingdom, Institute for Research in Immunology and Cancer, Universite de Montreal, Montreal, Quebec, Canada
⨯
Peter Ghazal,

Affiliations Division of Pathway Medicine, University of Edinburgh, Edinburgh, Midlothian, United Kingdom, SynthSys, Centre for Integrative Systems at Edinburgh, University of Edinburgh, Edinburgh, Midlothian, United Kingdom
⨯
Ralf Zimmer,

Affiliation Institute for Informatics, Ludwig-Maximilians-Universität München, München, Germany
⨯
Jürgen Haas

* E-mail: pip.beard@roslin.ed.ac.uk (PMB); juergen.haas@ed.ac.uk (JH)

Affiliation Division of Pathway Medicine, University of Edinburgh, Edinburgh, Midlothian, United Kingdom
⨯

A Loss of Function Analysis of Host Factors Influencing Vaccinia virus Replication by RNA Interference

Philippa M. Beard,
Samantha J. Griffiths,
Orland Gonzalez,
Ismar R. Haga,
Tali Pechenick Jowers,
Danielle K. Reynolds,
Jan Wildenhain,
Hille Tekotte,
Manfred Auer,
Mike Tyers

Published: June 5, 2014
https://doi.org/10.1371/journal.pone.0098431

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Small interfering RNA
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Vaccinia virus
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